Document Detail


Comparison of left ventricular function during interval versus steady-state exercise training in patients with chronic congestive heart failure.
MedLine Citation:
PMID:  9856924     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study sought to assess the safety of interval exercise training in patients with chronic congestive heart failure (CHF) with respect to left ventricular (LV) function. For effective rehabilitation in CHF, both aerobic capacity and muscle strength need to be improved. We have previously demonstrated in both coronary artery bypass surgery and patients with CHF that interval exercise training (IET) offers advantages over steady-state exercise training (SSET). However, because LV function during IET has not yet been studied, the safety of this method in CHF remains unclear. To assess LV function during IET and SSET, at the same average power output, 11 patients with stable CHF were compared with 9 stable coronary patients with minimal LV dysfunction (control group). Using first-pass radionuclide ventriculography, changes in LV function were assessed during work versus recovery phases, at temporally matched times between the fifth and sixteenth minute of IET and SSET. In CHF during IET, there were no significant variations in the parameters measured during work and/or recovery phases. During the course of both IET and SSET, there was a significant increase in LV ejection fraction (5 vs 4 U; p <0.05 each), accompanied by increased heart rate (6 vs 8 beats/min; p <0.05 each) and cardiac output (2.4 vs 1.8 L/min; p <0.01 and p <0.05). In CHF, the magnitude of change in LV ejection fraction during IET was similar to that seen in controls. Both LV ejection fraction and the clinical status in patients with CHF remained stable during IET. Because IET appears to be as safe as SSET with respect to LV function, IET can be recommended for exercise training in CHF to apply higher peripheral exercise stimuli and with no greater LV stress than during SSET.
Authors:
K Meyer; C Foster; N Georgakopoulos; R Hajric; S Westbrook; A Ellestad; K Tilman; D Fitzgerald; H Young; H Weinstein; H Roskamm
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  82     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1998 Dec 
Date Detail:
Created Date:  1998-12-21     Completed Date:  1998-12-21     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1382-7     Citation Subset:  AIM; IM    
Affiliation:
Herz-Zentrum, Bad Krozingen, Germany. meyerk@herzzentrum.de
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MeSH Terms
Descriptor/Qualifier:
Exercise Therapy*
Heart Failure / physiopathology*,  radionuclide imaging,  rehabilitation
Hemodynamics
Humans
Male
Middle Aged
Radionuclide Ventriculography
Stroke Volume
Ventricular Function, Left / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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