| Comparison of late survival in patients with cardiogenic shock due to right ventricular infarction versus left ventricular pump failure following primary percutaneous coronary intervention for ST-elevation acute myocardial infarction. | |
| | |
MedLine Citation:
|
PMID: 17293178 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This study compared late survival after primary percutaneous coronary intervention (PCI) in patients with cardiogenic shock due to right ventricular (RV) infarction versus left ventricular (LV) pump failure. Consecutive patients with ST-elevation myocardial infarction treated with primary PCI (n = 2,496) were prospectively enrolled in a registry from 1984 to 2004. Cardiogenic shock occurred before PCI in 189 patients (7.6%). Shock was attributed to predominant RV infarction when there was right coronary artery occlusion with preserved LV function and increased right atrial pressure. Patients with shock due to RV infarction (n = 30) versus LV pump failure (n = 136) had fewer previous infarctions (10% vs 29%, p = 0.03), less multivessel disease (20% vs 47%, p = 0.007), higher right atrial pressure (21 vs 16 mm, p = 0.003), and better LV ejection fraction (57% vs 32%, p <0.001). In-hospital mortality was lower with shock due to RV infarction (23% vs 50%, p = 0.01), and shock due to RV infarction was a significant independent predictor of late cardiac survival (hazard ratio 0.28, 95% confidence interval 0.13 to 0.62, p = 0.002). In conclusion, survival after primary PCI in patients with shock due to RV infarction is better than that in patients with shock due to LV pump failure. This is in contrast to most previous reports. Improved survival is likely related to lower risk profile and previously documented substantial recovery of RV function after primary PCI. |
| | |
Authors:
|
Bruce R Brodie; Thomas D Stuckey; Charles Hansen; Barbara H Bradshaw; William E Downey; Mark W Pulsipher |
Related Documents
:
|
19713678 - Extracorporeal shock wave therapy as a new and non-invasive angiogenic strategy. 2943528 - Response of hypertrophic heart myocardial glycogen to gik and hypovolemic shock. 6838398 - Assisted circulation in cardiac and respiratory insufficiency. 11558958 - Spongy cardiomyopathy in a neonate. 20485748 - Untargeted metabolic profiling reveals potential biomarkers in myocardial infarction an... 12923028 - Socioeconomic deprivation is a predictor of poor postoperative cardiovascular outcomes ... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2006-12-20 |
Journal Detail:
|
Title: The American journal of cardiology Volume: 99 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2007 Feb |
Date Detail:
|
Created Date: 2007-02-12 Completed Date: 2007-04-03 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
|
Languages: eng Pagination: 431-5 Citation Subset: AIM; IM |
Affiliation:
|
LeBauer Cardiovascular Research Foundation and Moses Cone Heart and Vascular Center, Greensboro, North Carolina, USA. bbrodie@triad.rr.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Angioplasty, Transluminal, Percutaneous Coronary* Chi-Square Distribution Female Hospital Mortality Humans Male Middle Aged Myocardial Infarction / complications*, mortality, physiopathology, therapy* Proportional Hazards Models Prospective Studies Registries Risk Factors Shock, Cardiogenic / etiology*, mortality, physiopathology Survival Rate Ventricular Dysfunction, Left / etiology*, mortality, physiopathology Ventricular Dysfunction, Right / complications*, mortality, physiopathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Tamoxifen induces permanent growth arrest through selective induction of apoptosis in growth plate c...
Next Document: Comparison of left ventricular ejection fraction and exercise capacity as predictors of two- and fiv...