| Comparison of lactate concentration determinations in ischemic and hypoxic rat brains by in vivo and in vitro 1H NMR spectroscopy. | |
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MedLine Citation:
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PMID: 3613957 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An experimental protocol for the quantitation of lactate is demonstrated for in vivo 1H NMR surface coil spectroscopy. The in vivo lactate concentration can be calculated by comparing the in vivo and in vitro ratios of lactate and N-acetylaspartate (NAA) NMR signals. With this protocol, approximately 25% of lactate present in the hypoxic or ischemic rat brain is observed by NMR. |
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Authors:
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L H Chang; B M Pereira; P R Weinstein; M A Keniry; J Murphy-Boesch; L Litt; T L James |
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Publication Detail:
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Type: Comparative Study; In Vitro; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Volume: 4 ISSN: 0740-3194 ISO Abbreviation: Magn Reson Med Publication Date: 1987 Jun |
Date Detail:
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Created Date: 1987-08-28 Completed Date: 1987-08-28 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8505245 Medline TA: Magn Reson Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 575-81 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Brain Chemistry* Hypoxia, Brain / metabolism* Ischemic Attack, Transient / metabolism* Lactates / analysis, metabolism* Magnetic Resonance Spectroscopy / diagnostic use* Rats |
| Grant Support | |
ID/Acronym/Agency:
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NS 22022-02/NS/NINDS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Lactates |
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