Document Detail

Comparison of intracytoplasmic sperm injection outcomes between spermatozoa retrieved from testicular biopsy and from ejaculation in cryptozoospermic men.
MedLine Citation:
PMID:  22077321     Owner:  NLM     Status:  Publisher    
The infrequent presence of spermatozoa in cryptozoospermic men ejaculate is a limiting factor in the treatment of them. Sometimes, this consideration impels us to apply meticulous microscopic search in ejaculate or testicular sperm extraction (TESE) method. The aim of this study was to assess putative effectiveness of sperm origin, ejaculated or testicular, in cryptozoospermia treatment. In this context, were evaluated intracytoplasmic sperm injection (ICSI) outcomes in two parameters including fertilisation rate (2PN) and embryo quality, independently. We compared the outcome in two groups: patients who underwent ejaculate/ICSI and ones who underwent TESE/ICSI process. Nineteen ICSI cycles performed with testicular spermatozoa and the rest of cycles (n = 208) carried out with ejaculated spermatozoa. Result analysis showed similar fertilisation rate between testicular and ejaculated spermatozoa (respectively, 60% versus 68%, P ≥ 0.05). Also, on the other hand, embryo quality did not show significant differences between two groups, except grade A with low significance. With regard to almost equal performance of both methods in results and being invasive of TESE as surgical sperm retrieval method, the use of ejaculated sperm more than testicular sperm should be recommended in patients with cryptozoospermia whenever possible.
N Amirjannati; H Heidari-Vala; M A Akhondi; S H Hosseini Jadda; K Kamali; M R Sadeghi
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-12
Journal Detail:
Title:  Andrologia     Volume:  -     ISSN:  1439-0271     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0423506     Medline TA:  Andrologia     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 Blackwell Verlag GmbH.
 Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran  Nanobiotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran  Monoclonal Antibody Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
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