| Comparison of inhalation inductions with xenon and sevoflurane. | |
| | |
MedLine Citation:
|
PMID: 9366936 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Xenon is an odorless gas with low blood-gas solubility coefficient and without occupational and environmental hazards. This investigation was performed to evaluate the speed of induction, and respiratory and cardiovascular reactions to inhalation induction with xenon compared to an equianesthetic concentration of sevoflurane. METHOD: Twenty-four adult ASA 1-2 patients premedicated with 0.05 mg/kg of midazolam were instructed to take vital capacity breaths of 1 minimum alveolar concentration (MAC) of either xenon or sevoflurane until they lost consciousness. Induction time, total ventilatory volume, tidal volume, respiratory rate, minute ventilation, end-tidal MAC fraction, cardiovascular parameters and oxygen saturation were recorded. The patients were interviewed on the following day to evaluate their acceptability rating of the inhalation inductions. RESULTS: Compared to equianesthetic sevoflurane, xenon produced a faster induction of anesthesia (147 +/- 59 versus 71 +/- 21 s, respectively) with smaller decreases in respiratory rate, tidal volume and minute ventilation. Both agents showed comparable cardiovascular stability and oxygen saturation during induction. One patient in the sevoflurane group had breath-holding and movements of extremities and another had only breath-holding. No patients in the xenon group experienced any complications. CONCLUSION: Xenon produced a faster induction of anesthesia without any complications than sevoflurane. Xenon had smaller decreases in tidal volume and respiratory rate during induction than sevoflurane. Xenon might offer an alternative to sevoflurane for an inhalation induction. |
| | |
Authors:
|
Y Nakata; T Goto; S Morita |
Related Documents
:
|
18295616 - Fluoroscopic analysis of lumbar epidural contrast spread after lumbar interlaminar inje... 1640366 - Experimental studies of transient mass transfer and reaction in the liver: interpretati... 1536396 - Effect of fentanyl on the circulatory responses to orotracheal fibreoptic intubation. 23133756 - Blood flow restricted exercise and vascular function. 18502686 - Exercise training prevents beta-adrenergic hyperactivity-induced myocardial hypertrophy... 3766596 - Prognostic information from early post-infarction exercise testing. |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
|
Title: Acta anaesthesiologica Scandinavica Volume: 41 ISSN: 0001-5172 ISO Abbreviation: Acta Anaesthesiol Scand Publication Date: 1997 Oct |
Date Detail:
|
Created Date: 1997-12-18 Completed Date: 1997-12-18 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0370270 Medline TA: Acta Anaesthesiol Scand Country: DENMARK |
Other Details:
|
Languages: eng Pagination: 1157-61 Citation Subset: IM |
Affiliation:
|
Department of Anesthesia, Teikyo University School of Medicine Ichihara Hospital, Chiba, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Anesthesia, Inhalation* Anesthetics, Inhalation* Blood Pressure / drug effects Double-Blind Method Ethers* Female Heart Rate / drug effects Humans Male Methyl Ethers* Respiratory System / drug effects Xenon* |
| Chemical | |
Reg. No./Substance:
|
0/Anesthetics, Inhalation; 0/Ethers; 0/Methyl Ethers; 28523-86-6/sevoflurane; 7440-63-3/Xenon |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Ropivacaine 7.5 mg/ml for elective caesarean section. A clinical and pharmacokinetic comparison of 1...
Next Document: Desflurane increases brain tissue oxygenation and pH.