| Comparison of in-vitro maturation cycles with and without in-vivo matured oocytes retrieved. | |
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MedLine Citation:
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PMID: 18616892 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study compared the embryological characteristics and clinical outcome of in-vitro maturation (IVM) treatment cycles with and without in-vivo matured oocytes collected following human chorionic gonadotrophin (HCG) priming. The patients were administered 10,000 IU of HCG subcutaneously when endometrial thickness reached > or =6 mm and oocyte collection was performed 35-36 h after HCG administration. The clinical outcome and embryological aspects were analysed between IVM cycles with (group 1) and without (group 2) in-vivo matured oocytes. In group 1, three (range 1-12) in-vivo matured oocytes per patient were retrieved on average. The number of good quality embryos derived from in-vivo matured oocytes in group 1 was significantly higher than those derived from in-vitro matured oocytes in group 1 and group 2 (P < 0.05). However, there was no difference between the number of good quality embryos produced from in-vitro matured oocytes in the two groups. There were 12 clinical pregnancies (40.0%) in group 1, and seven pregnancies (23.3%) in group 2. These results suggest that IVM cycles with in-vivo matured oocytes resulted in a good clinical pregnancy rate, which could be explained by the superior quality of embryos derived from the in-vivo matured oocytes. |
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Authors:
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Weon-Young Son; Jin-Tae Chung; Ezgi Demirtas; Hananel Holzer; Camille Sylvestre; William Buckett; Ri-Cheng Chian; Seang Lin Tan |
Publication Detail:
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Type: Comparative Study; In Vitro; Journal Article |
Journal Detail:
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Title: Reproductive biomedicine online Volume: 17 ISSN: 1472-6491 ISO Abbreviation: Reprod. Biomed. Online Publication Date: 2008 Jul |
Date Detail:
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Created Date: 2008-07-11 Completed Date: 2008-08-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101122473 Medline TA: Reprod Biomed Online Country: England |
Other Details:
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Languages: eng Pagination: 59-67 Citation Subset: IM |
Affiliation:
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McGill Reproductive Centre, Department of Obstetrics and Gynecology, Royal Victoria Hospital, McGill University, Montreal, Quebec H3A 1A1, Canada. weon-young.son@muhc.mcgill.ca |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Chorionic Gonadotropin / metabolism Cumulus Cells / cytology Embryo Transfer Endometrium / pathology Female Fertilization in Vitro / methods Humans Oocytes / metabolism* Ovulation Induction Pregnancy Pregnancy Outcome Pregnancy Rate Retrospective Studies Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Chorionic Gonadotropin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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