Document Detail

Comparison of in vitro fertilization versus intracytoplasmic sperm injection in extremely low oocyte retrieval cycles.
MedLine Citation:
PMID:  19108823     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare the results of IVF and intracytoplasmic sperm injection (ICSI) in extremely low oocyte retrieval cycles. DESIGN: Case-control study. SETTING: An IVF laboratory in a university hospital in Taiwan. PATIENT(S): Between January 2003 and December 2007, infertile couples with one, two, or three oocytes per retrieval were divided into two groups: 56 IVF cycles based on 28 demographic characteristics from the ICSI group. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Fertilization rate, cycle cancellation rate, clinical pregnancy rate, and implantation rate per transfer. RESULT(S): The normal fertilization rate was significantly higher after ICSI than after standard IVF (86.4% vs. 69.3%). The cycle cancellation and complete fertilization failure rates were comparable between the two groups. The clinical pregnancy rate per transfer (38.5% vs. 21.6%), implantation rate (23.5% vs. 11.1%), and live birth rate per transfer (30.8% vs. 13.7%) had a favorable trend, but no statistically significant differences, in the ICSI group compared with the IVF group. CONCLUSION(S): A higher normal fertilization rate can be achieved by ICSI in comparison with conventional IVF in extremely low oocyte retrieval cycles.
Yu-Che Ou; Kuo-Chung Lan; Fu-Jen Huang; Fu-Tsai Kung; Ting-Hsun Lan; Shiuh Young Chang
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-12-23
Journal Detail:
Title:  Fertility and sterility     Volume:  93     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-01-27     Completed Date:  2010-02-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  96-100     Citation Subset:  IM    
Copyright Information:
Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, Niaosung Hsiang, Kaohsiung, Taiwan.
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MeSH Terms
Case-Control Studies
Embryo Implantation
Fertilization in Vitro*
Infertility / therapy*
Live Birth
Middle Aged
Oocyte Retrieval*
Ovulation Induction*
Pregnancy Rate
Sperm Injections, Intracytoplasmic*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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