Document Detail


Comparison of impedance cardiography to direct Fick and thermodilution cardiac output determination in pulmonary arterial hypertension.
MedLine Citation:
PMID:  15073478     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cardiac output (CO) is an important diagnostic and prognostic tool for patients with ventricular dysfunction. Pulmonary hypertension patients undergo invasive right heart catheterization to determine pulmonary vascular and cardiac hemodynamics. Thermodilution (TD) and direct Fick method are the most common methods of CO determination but are costly and may be associated with complications. The latest generation of impedance cardiography (ICG) provides noninvasive estimation of CO and is now validated. The purpose of this study was to compare ICG measurement of CO to TD and direct Fick in pulmonary hypertension patients. Thirty-nine enrolled patients were analyzed: 44% were male and average age was 50.8+/-17.4 years. Results for bias and precision of cardiac index were as follows: ICG vs. Fick (-0.13 L/min/m2 and 0.46 L/min/m2), TD vs. Fick (0.10 L/min/m2 and 0.41 L/min/m2), ICG vs. TD (respectively, with a 95% level of agreement between -0.72 and 0.92 L/min/m2; CO correlation of ICG vs. Fick, TD vs. Fick, and ICG vs. TD was 0.84, 0.89, and 0.80, respectively). ICG provides an accurate, useful, and cost-effective method for determining CO in pulmonary hypertension patients, and is a potential tool for following responses to therapeutic interventions.
Authors:
Gordon L Yung; Peter F Fedullo; Katie Kinninger; Wayne Johnson; Richard N Channick
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Congestive heart failure (Greenwich, Conn.)     Volume:  10     ISSN:  1527-5299     ISO Abbreviation:  Congest Heart Fail     Publication Date:    2004 Mar-Apr
Date Detail:
Created Date:  2004-04-09     Completed Date:  2004-07-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9714174     Medline TA:  Congest Heart Fail     Country:  United States    
Other Details:
Languages:  eng     Pagination:  7-10     Citation Subset:  IM    
Affiliation:
Division of Pulmonary and Critical Care Medicine, University of California San Diego Medical Center, San Diego, CA 92103-8373, USA. gyung@ucsd.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Cardiac Output / physiology*
Cardiography, Impedance / methods*
Female
Hemodynamics
Humans
Hypertension, Pulmonary / diagnosis*,  physiopathology
Male
Middle Aged
Oxygen Consumption / physiology
Thermodilution / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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