Document Detail

Comparison of immediate and mid-term results of mitral balloon valvotomy in children and adolescents with those in adults.
MedLine Citation:
PMID:  14765840     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND AIM OF THE STUDY: The study aim was to evaluate and compare the hemodynamic benefits of mitral balloon valvotomy (MBV) in young (child/adolescent) and older (adult) patients with severe mitral stenosis.
METHODS: The younger group comprised 61 patients (mean age 17 +/- 3 years), and the older group 264 patients (mean age 35 +/- 10 years). All patients underwent MBV using an Inoue balloon to treat symptomatic and severe mitral stenosis. The long-term follow up of both groups was monitored on a comparative basis.
RESULTS: The success rate of MBV was similar in both groups (95% in younger patients, 96% in older patients) (p = 0.36). Mitral valve area (MVA) was increased from 0.8 +/- 0.2 to 2.0 +/- 0.3 cm2 in the younger group, and from 0.8 +/- 0.3 to 1.9 +/- 0.3 cm2 in the older group. The mean mitral valve gradient was decreased significantly both in the younger group (from 13 +/- 5 to 5 +/- 2 mmHg) and older group (from 12 +/- 5 to 5 +/- 3 mmHg) (p < 0.001). Both groups had similar MVA and mean gradient at baseline and follow up. At follow up (mean 37 +/- 27 months), MVA monitored by Doppler echocardiography remained at 1.7 +/- 0.4 and 1.6 +/- 0.4 cm2 (p = 0.08). Similarly, the mitral valve mean gradient remained stable (p = 0.92). Severe mitral regurgitation developed in one younger patient, and in seven older patients (p = 0.66). Two cases of tamponade occurred in each group, and one older patient suffered a transient stroke. There was no mortality in either group.
CONCLUSION: In patients with rheumatic mitral stenosis, the outcome of MBV in children and adolescents was at least comparable with that in adults. In addition, the benefits were similar in each age group on completion of follow up.
Abdulhalim Jamaluddeen Kinsara; Mohamed Eid Fawzi; Faisal Abdulkader Batwa
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article    
Journal Detail:
Title:  The Journal of heart valve disease     Volume:  13     ISSN:  0966-8519     ISO Abbreviation:  J. Heart Valve Dis.     Publication Date:  2004 Jan 
Date Detail:
Created Date:  2004-02-09     Completed Date:  2004-09-02     Revised Date:  2010-12-01    
Medline Journal Info:
Nlm Unique ID:  9312096     Medline TA:  J Heart Valve Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  53-6     Citation Subset:  IM    
Department of Cardiovascular Diseases, King Khalid National Guard Hospital, Jeddah, Saudi Arabia.
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MeSH Terms
Balloon Dilation* / adverse effects
Balloon Occlusion*
Follow-Up Studies
Mitral Valve Stenosis / therapy*
Postoperative Complications / epidemiology
Severity of Illness Index
Time Factors

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