Document Detail


Comparison of ileoanal pouch and rectal function measured by barostat.
MedLine Citation:
PMID:  11330405     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to compare pouch and rectal sensory and motor characteristics and to assess the influence of a meal on pouch tone and motility. Fifteen patients with an ileoanal J-pouch, with adequate pouch function and 12 healthy controls were studied. Visceral compliance was assessed using an electronic barostat by a pressure distension procedure, during which also sensitivity was scored by visual analog scales (VAS). The response to a meal was assessed during set pressure. Pouch and rectal compliance were not significantly different (9.3+/-0.7 vs 10.6+/-1.1 ml/mm Hg). VAS score for urge at 28 mm Hg was reduced in patients: 2.4+/-0.5 cm vs 4.7+/-0.9 cm in controls (P < 0.05). The postprandial decrease in intra-bag volume was more pronounced in patients (44+/-11%) than in controls (9+/-6%, P < 0.01). Postprandial phasic contractions were also more pronounced in patients. In conclusion, compliance is not significantly different between ileoanal pouch and rectum; differences in sensitivity reach significance only at high pressure. Significant differences were especially observed in the postprandial state with an increase in tone and frequency of phasic contractions in pouch patients.
Authors:
J Steens; C Penning; W A Bemelman; G Griffioen; R A Van Hogezand; W J Meijerink; C B Lamers; A A Masclee
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  46     ISSN:  0163-2116     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2001-05-01     Completed Date:  2001-07-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  731-8     Citation Subset:  AIM; IM    
Affiliation:
Department of Gastroenterology-Hepatology, Leiden University Medical Center, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Adult
Compliance
Female
Gastrointestinal Motility
Humans
Male
Muscle Tonus
Postprandial Period
Pressure
Proctocolectomy, Restorative*
Rectum / physiology*
Sensation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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