|Comparison of hemodynamic effects of lidocaine, prilocaine and mepivacaine solutions without vasoconstrictor in hypertensive patients.|
|PMID: 20835569 Owner: NLM Status: MEDLINE|
|OBJECTIVE: Local anesthetic solutions with vasoconstrictors are not contraindicated in hypertensive patients, but due to their hemodynamic effects, local anesthetics without vasoconstrictors are mainly preferred by the clinicians. The aim of this study was to compare hemodynamic effects of three different local anesthetics without vasoconstrictors during tooth extraction in hypertensive patients.
MATERIAL AND METHODS: Sixty-five mandibular molars and premolars were extracted in 60 hypertensive patients (29 females and 31 males; mean age: 66.95 ± 10.87 years; range: 38 to 86 years old). Inferior alveolar and buccal nerve blocks were performed with 2% lidocaine hydrochloride (HCl), 2% prilocaine HCl or 3% mepivacaine HCl without vasoconstrictor. Hemodynamic parameters namely systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), saturation rate (SR), rate pressure product (RPP) and pressure rate quotient (PRQ) were investigated before and at different intervals after anesthetic injection.
RESULTS: The hemodynamic effects of the three agents were similar to each other, although some significance was observed for DBP, MAP, RPP and PRQ values in the lidocaine, prilocaine and mepivacaine groups.
CONCLUSION: Lidocaine, prilocaine and mepivacaine solutions without vasoconstrictor can be safely used in hypertensive patients. It is advisable that dental practitioners select anesthetic solutions for hypertensive patients considering their cardiovascular effects in order to provide patient comfort and safety.
|Bahadir Ezmek; Ahmet Arslan; Cagri Delilbasi; Kemal Sencift|
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|Type: Comparative Study; Journal Article|
|Title: Journal of applied oral science : revista FOB Volume: 18 ISSN: 1678-7765 ISO Abbreviation: J Appl Oral Sci Publication Date: 2010 Jul-Aug|
|Created Date: 2010-09-13 Completed Date: 2010-12-23 Revised Date: -|
Medline Journal Info:
|Nlm Unique ID: 101189774 Medline TA: J Appl Oral Sci Country: Brazil|
|Languages: eng Pagination: 354-9 Citation Subset: D; IM|
|Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Yeditepe University, Istanbul, Turkey.|
|APA/MLA Format Download EndNote Download BibTex|
Aged, 80 and over
Anesthetics, Local / administration & dosage*
Bicuspid / surgery
Blood Pressure / drug effects
Calcium Channel Blockers / therapeutic use
Cheek / innervation
Heart Rate / drug effects
Hemodynamics / drug effects*
Hypertension / drug therapy, physiopathology*
Lidocaine / administration & dosage*
Mandibular Nerve / drug effects
Mepivacaine / administration & dosage*
Molar / surgery
Nerve Block / methods
Oxygen / blood
Prilocaine / administration & dosage*
Vasoconstrictor Agents / administration & dosage
|0/Adrenergic beta-Antagonists; 0/Anesthetics, Local; 0/Calcium Channel Blockers; 0/Vasoconstrictor Agents; 137-58-6/Lidocaine; 721-50-6/Prilocaine; 7782-44-7/Oxygen; 96-88-8/Mepivacaine|
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