| Comparison of hemodynamic effects of lidocaine, prilocaine and mepivacaine solutions without vasoconstrictor in hypertensive patients. | |
| | |
MedLine Citation:
|
PMID: 20835569 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: Local anesthetic solutions with vasoconstrictors are not contraindicated in hypertensive patients, but due to their hemodynamic effects, local anesthetics without vasoconstrictors are mainly preferred by the clinicians. The aim of this study was to compare hemodynamic effects of three different local anesthetics without vasoconstrictors during tooth extraction in hypertensive patients. MATERIAL AND METHODS: Sixty-five mandibular molars and premolars were extracted in 60 hypertensive patients (29 females and 31 males; mean age: 66.95 ± 10.87 years; range: 38 to 86 years old). Inferior alveolar and buccal nerve blocks were performed with 2% lidocaine hydrochloride (HCl), 2% prilocaine HCl or 3% mepivacaine HCl without vasoconstrictor. Hemodynamic parameters namely systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), saturation rate (SR), rate pressure product (RPP) and pressure rate quotient (PRQ) were investigated before and at different intervals after anesthetic injection. RESULTS: The hemodynamic effects of the three agents were similar to each other, although some significance was observed for DBP, MAP, RPP and PRQ values in the lidocaine, prilocaine and mepivacaine groups. CONCLUSION: Lidocaine, prilocaine and mepivacaine solutions without vasoconstrictor can be safely used in hypertensive patients. It is advisable that dental practitioners select anesthetic solutions for hypertensive patients considering their cardiovascular effects in order to provide patient comfort and safety. |
| | |
Authors:
|
Bahadir Ezmek; Ahmet Arslan; Cagri Delilbasi; Kemal Sencift |
Related Documents
:
|
10652909 - Hypertension in elderly--an overview. 15592569 - Does the reduction in systolic blood pressure alone explain the regression of left vent... 1500129 - Blood pressure levels in south indian adolescents. 19470869 - Blood pressure variables and cardiovascular risk: new findings from advance. 12756409 - Mean arterial pressure and pulse pressure are associated with different clinical parame... 14715189 - Mechanism(s) of selective systolic blood pressure reduction after a low-dose combinatio... 14971569 - Rotatory nystagmus synchronous with heartbeat: a treatable form of nystagmus. 8067419 - Ratiometric methodology for nad(p)h measurement in the perfused rat heart using surface... 19870879 - Osmotic pressure study of protein fractions in normal and in nephrotic subjects. |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Journal of applied oral science : revista FOB Volume: 18 ISSN: 1678-7765 ISO Abbreviation: J Appl Oral Sci Publication Date: 2010 Jul-Aug |
Date Detail:
|
Created Date: 2010-09-13 Completed Date: 2010-12-23 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101189774 Medline TA: J Appl Oral Sci Country: Brazil |
Other Details:
|
Languages: eng Pagination: 354-9 Citation Subset: D; IM |
Affiliation:
|
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Yeditepe University, Istanbul, Turkey. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adrenergic beta-Antagonists
/
therapeutic use Adult Aged Aged, 80 and over Anesthetics, Local / administration & dosage* Bicuspid / surgery Blood Pressure / drug effects Calcium Channel Blockers / therapeutic use Cheek / innervation Female Heart Rate / drug effects Hemodynamics / drug effects* Humans Hypertension / drug therapy, physiopathology* Lidocaine / administration & dosage* Male Mandibular Nerve / drug effects Mepivacaine / administration & dosage* Middle Aged Molar / surgery Nerve Block / methods Oxygen / blood Prilocaine / administration & dosage* Tooth Extraction Vasoconstrictor Agents / administration & dosage |
| Chemical | |
Reg. No./Substance:
|
0/Adrenergic beta-Antagonists; 0/Anesthetics, Local; 0/Calcium Channel Blockers; 0/Vasoconstrictor Agents; 137-58-6/Lidocaine; 721-50-6/Prilocaine; 7782-44-7/Oxygen; 96-88-8/Mepivacaine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Bone regeneration in surgically created defects filled with autogenous bone: an epifluorescence micr...
Next Document: Influence of ferrule preparation with or without glass fiber post on fracture resistance of endodont...