Document Detail


Comparison of gastric emptying times in healthy cats simultaneously evaluated with radiopaque markers and nuclear scintigraphy.
MedLine Citation:
PMID:  10024002     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Gastric emptying in 18 healthy cats was assessed simultaneously using scintigraphy and barium-impregnated polyethylene spheres (BIPS). Canned Prescription Diet Feline c/d (Hill's Pet Nutrition, Inc., Topeka, KS) labeled with 99mTc-disofenin (Hepatolite, DuPont Merck Pharmaceutical Co., Billerica, Mass.) was fed on four separate days. Scintigraphic images were obtained at time 0 and then every 30 minutes to 6 hours. On the fourth scan day, 30 small (1.5 mm) and 10 large (5 mm) BIPS (Chemstock Animal Health Ltd., Christchurch, New Zealand) were mixed with the labeled meal, and in addition to scintigraphy, radiographs were made at 60-minute intervals for 6 hours. Gastric emptying was 11 to 15% slower on the day of simultaneous radiography as compared with the 3 days when only scintigraphy was performed (p < or = .05). Percentage retention of 1.5 mm BIPS in the stomach was significantly greater than the percentage retained gastric activity at hours 1, 2, 3, 4, 5, and 6 (p < or = .05). BIPS were clustered in the pyloric region of the stomach by 3 hours in all cats. In 10/18 animals, all BIPS were retained in pyloric region of the stomach at 6 hours, despite observable decreased size of the gastric silhouette and < or =15% retained gastric activity. In conclusion, gastric emptying of 1.5-mm BIPS does not parallel gastric emptying of 99mTc-disofenin labeled canned Prescription Diet Feline c/d. Stress associated with radiography may delay gastric emptying. Diet type should be considered when evaluating clinical radiographic studies where BIPS have been used.
Authors:
J M Goggin; J J Hoskinson; C A Kirk; D Jewell; M D Butine
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association     Volume:  40     ISSN:  1058-8183     ISO Abbreviation:  Vet Radiol Ultrasound     Publication Date:    1999 Jan-Feb
Date Detail:
Created Date:  1999-04-21     Completed Date:  1999-04-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9209635     Medline TA:  Vet Radiol Ultrasound     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  89-95     Citation Subset:  IM    
Affiliation:
Department of Clinical Sciences, Kansas State University, College of Veterinary Medicine, Manhattan 66506-5606, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Barium / diagnostic use
Cats / physiology*
Contrast Media
Female
Gastric Emptying / physiology*
Male
Polyethylenes / diagnostic use
Radiography / methods,  veterinary*
Radionuclide Imaging / methods,  veterinary*
Technetium Tc 99m Disofenin / diagnostic use
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Polyethylenes; 0/Technetium Tc 99m Disofenin; 7440-39-3/Barium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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