| Comparison of gadolinium-EOB-DTPA-enhanced and diffusion-weighted liver MRI for detection of small hepatic metastases. | |
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MedLine Citation:
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PMID: 20563726 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To compare the accuracy of gadolinium ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced MRI with that of diffusion-weighted MRI (DWI) in the detection of small hepatic metastases (2 cm or smaller). METHODS: Forty-five patients underwent abdominal MRI at 3 T, including T1-weighted imaging (T1WI), T2-weighted imaging (T2WI), heavily T2WI (HASTE), DWI with a b-value of 500 s/mm(2) and contrast-enhanced MRI with Gd-EOB-DTPA. Two groups were assigned and compared: group A (T1WI, T2WI, HASTE and contrast-enhanced study with Gd-EOB-DTPA), and group B (T1WI, T2WI, HASTE and DWI). Two observers independently interpreted the images obtained in a random order. For all hepatic metastases, the diagnostic performance using each imaging set was evaluated by receiver-operating characteristic (ROC) curve analysis. RESULTS: A total of 51 hepatic metastases were confirmed. The area under the ROC curve (Az) of group A was larger than that of group B, and the difference in the mean Az values between the two image sets was statistically significant, whereas, there were three metastases that lay near thin vessels or among multiple cysts and were better visualised in group B than in group A. CONCLUSION: Gd-EOB-DTPA-enhanced MRI showed higher accuracy in the detection of small metastases than DWI. |
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Authors:
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Kotaro Shimada; Hiroyoshi Isoda; Yuusuke Hirokawa; Shigeki Arizono; Toshiya Shibata; Kaori Togashi |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2010-06-20 |
Journal Detail:
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Title: European radiology Volume: 20 ISSN: 1432-1084 ISO Abbreviation: Eur Radiol Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-04 Completed Date: 2011-01-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 2690-8 Citation Subset: IM |
Affiliation:
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Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan. kotaro@kuhp.kyoto-u.ac.jp |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Contrast Media* Diffusion Magnetic Resonance Imaging* Female Gadolinium DTPA / diagnostic use* Humans Liver Neoplasms / diagnosis*, secondary* Magnetic Resonance Imaging* Male Middle Aged Predictive Value of Tests ROC Curve Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/gadolinium ethoxybenzyl DTPA; 80529-93-7/Gadolinium DTPA |
| Comments/Corrections | |
Comment In:
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Eur Radiol. 2011 Jan;21(1):150
[PMID:
20694470
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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