| Comparison of five methods for oxacillin susceptibility testing of Staphylococcus aureus isolates from cystic fibrosis patients. | |
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MedLine Citation:
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PMID: 23152311 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Methicillin-resistant Staphylococcus aureus (MRSA) are now a worldwide problem. Cystic fibrosis (CF) patients are commonly colonized and infected by MRSA. Accurate oxacillin susceptibility testing is mandatory for the adequate management of these patients. We performed a comparison of the accuracy of different tests in CF isolates, including methicillin-susceptible S. aureus and MRSA with different SCCmec types, and using the mecA gene as the gold-standard. The sensitivity and specificity of oxacillin disc, Etest, and oxacillin agar screening plate were 100%. Sensitivity of the cefoxitin disc was 85% and specificity was 100%. For clinically relevant isolates, laboratories may consider the use of a combination of two phenotypic methods. |
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Authors:
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Marcelo J Mimica; Rozane L Carvalho; Eitan N Berezin; Neiva Damaceno; Hélio H Caiaffa-Filho |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Revista do Instituto de Medicina Tropical de São Paulo Volume: 54 ISSN: 1678-9946 ISO Abbreviation: Rev. Inst. Med. Trop. Sao Paulo Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2012-11-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7507484 Medline TA: Rev Inst Med Trop Sao Paulo Country: Brazil |
Other Details:
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Languages: eng Pagination: 305-6 Citation Subset: IM |
Affiliation:
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Division of Microbiology, Department of Pathology, Santa Casa School of Medicine, São Paulo, SP, Brazil. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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