Document Detail

Comparison of fetal myocardial contractility before and after laser photocoagulation of communicating vessels in twin-to-twin transfusion syndrome.
MedLine Citation:
PMID:  24834706     Owner:  NLM     Status:  In-Process    
OBJECTIVES: To evaluate changes in myocardial contractility that occur after selective laser photocoagulation of communicating vessels (SLPCV) in fetuses from pregnancies complicated with twin-to-twin transfusion syndrome (TTTS).
METHODS: The study included 51 pregnant women between 16 and 26 weeks of gestation who underwent SLPCV due to TTTS. Ultrasonography was performed before SLPCV and on postoperative day 1, 3(4) and 7. Fetal heart contractility in both fetuses was evaluated by determining the shortening fractions of the left and right ventricles (FS LV and FS RV), and the myocardial performance index (Tei-Index).
RESULTS: There was a significant increase in postoperative FS LV and FS RV in recipients (from 35.7% to 44%, P = 0.037 and from 27.6% to 32.9%, P = 0.021, respectively). Pre-operative Tei-Index values for both the left (0.55) and right ventricle (0.6) were above normal. The mean postoperative Tei-Index for the left ventricle decreased significantly to 0.49 (P = 0.011), while no significant change was observed in the right ventricle (0.57). No significant differences between pre- and postoperative FS and Tei-Index values were noted in the donors.
CONCLUSIONS: SLPCV is reflected by a significantly increased myocardial contractility in recipients.
Katarzyna Leszczyńska; Krzysztof Preis; Małgorzata Swiatkowska-Freund; Zofia Pankrac
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ginekologia polska     Volume:  85     ISSN:  0017-0011     ISO Abbreviation:  Ginekol. Pol.     Publication Date:  2014 Apr 
Date Detail:
Created Date:  2014-05-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0374641     Medline TA:  Ginekol Pol     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  283-6     Citation Subset:  IM    
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