Document Detail

Comparison of the femtosecond laser and mechanical keratome for laser in situ keratomileusis.
MedLine Citation:
PMID:  19001213     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare clinical outcomes between fellow eyes randomized to femtosecond laser-created flaps (femtosecond group) or mechanical keratome-created flaps (mechanical group) during wavefront-guided laser in situ keratomileusis. DESIGN: Prospective, randomized, comparative clinical study. MAIN OUTCOME MEASURES: Efficacy, safety, predictability, stability, changes in corneal optical aberrations, and low-contrast visual acuity before and 1 week and 1, 3, 6, and 12 months after surgery. RESULTS: Forty-three patients underwent evaluation in this study. One month after surgery, the mean (SD) spherical equivalent was -0.15 (0.30) diopters (D) for the femtosecond group and -0.12 (0.29) D for the mechanical group (differences were not statistically significant). Twelve months after surgery, 39 eyes (98%) in the femtosecond group had uncorrected visual acuity of 20/20 or better compared with 37 (95%) in the mechanical group. The femtosecond group had fewer high-order, spherical, and coma aberrations and more trefoil aberrations than the mechanical group at 1 month (P = .55), 3 months (P = .05), 6 months (P = .33), and 12 months (P = .48) after surgery. At 25% contrast, the femtosecond group had gains at 1 month (P = .01) and 6 months (P = .008) after surgery. CONCLUSION: Twelve months after keratomileusis, clinical outcomes were similar for both groups.
Annie Chan; Judy Ou; Edward E Manche
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Archives of ophthalmology     Volume:  126     ISSN:  1538-3601     ISO Abbreviation:  Arch. Ophthalmol.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-11-12     Completed Date:  2008-11-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7706534     Medline TA:  Arch Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1484-90     Citation Subset:  AIM; IM    
Department of Ophthalmology, Stanford University School of Medicine, Stanford, CA 94305, USA.
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MeSH Terms
Corneal Stroma / pathology,  surgery*
Follow-Up Studies
Intraoperative Complications
Keratomileusis, Laser In Situ / methods*
Lasers, Excimer / therapeutic use*
Middle Aged
Myopia / physiopathology,  surgery*
Postoperative Complications
Prospective Studies
Surgical Flaps*
Treatment Outcome
Visual Acuity / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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