| Comparison of femoral blood gases and muscle near-infrared spectroscopy at exercise onset in humans. | |
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MedLine Citation:
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PMID: 9931209 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We hypothesized that near-infrared spectroscopy (NIRS) measures of hemoglobin and/or myoglobin O2 saturation (IR-SO2) in the vascular bed of exercising muscle would parallel changes in femoral venous O2 saturation (SfvO2) at the onset of leg-kicking exercise in humans. Six healthy subjects performed transitions from rest to 48 +/- 3 (SE)-W two-legged kicking exercise while breathing 14, 21, or 70% inspired O2. IR-SO2 was measured over the vastus lateralis muscle continuously during all tests, and femoral venous and radial artery blood samples were drawn simultaneously during rest and during 5 min of exercise. In all gas-breathing conditions, there was a rapid decrease in both IR-SO2 and SfvO2 at the onset of moderate-intensity leg-kicking exercise. Although SfvO2 remained at low levels throughout exercise, IR-SO2 increased significantly after the first minute of exercise in both normoxia and hyperoxia. Contrary to the hypothesis, these data show that NIRS does not provide a reliable estimate of hemoglobin and/or O2 saturation as reflected by direct femoral vein sampling. |
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Authors:
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M J MacDonald; M A Tarnopolsky; H J Green; R L Hughson |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of applied physiology (Bethesda, Md. : 1985) Volume: 86 ISSN: 8750-7587 ISO Abbreviation: J. Appl. Physiol. Publication Date: 1999 Feb |
Date Detail:
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Created Date: 1999-03-22 Completed Date: 1999-03-22 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8502536 Medline TA: J Appl Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 687-93 Citation Subset: IM; S |
Affiliation:
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Department of Kinesiology, University of Waterloo, Waterloo N2L 3G1, Ontario, Canada L8S 4L8. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anaerobic Threshold Anoxia / physiopathology Blood Gas Analysis* Exercise / physiology* Exercise Test Female Femoral Vein / metabolism* Heart Rate / physiology Humans Male Muscle, Skeletal / metabolism* Oxygen Consumption / physiology Radial Artery / physiology Spectroscopy, Near-Infrared |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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