| Comparison of estimated creatinine clearance among five formulae (Cockroft-Gault, Jelliffe, Sanaka, simplified 4-variable MDRD and DAF) and the 24hours-urine-collection creatinine clearance. | |
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MedLine Citation:
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PMID: 20596264 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Background: GFR estimation is of major importance in everyday clinical practice. Usually it is done using one of the many eGFR equations available. In this study we compared in our population four widespread eGFR equations and our own empirical eGFR, with creatinine clearance calculated through a timed urine collection.Patients and methods: We collected laboratory data of 907 patients from our clinic and outpatient department through a ten-year period and statistically compared the eGFR results between them and with the timed urine collection creatinine clearances.Results: All eGFR equations gave acceptable approximations to the timed urine collection creatinine clearances. However, in different subpopulations some equations did better than others, without any clear advantage of any equation overall. Surprisingly, our empirical equation named DAF also gave acceptable approximations regardless of age, weight and sex of the patient.Conclusions: In our population our empirical eGFR method (DAF) gave satisfactory results regarding the monitoring of renal function, compared with four other eGFR methods. We suggest that it could provide a very fast and easy to use means of eGFR calculation. |
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Authors:
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A Diamandopoulos; P Goudas; A Arvanitis |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Hippokratia Volume: 14 ISSN: 1790-8019 ISO Abbreviation: Hippokratia Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-07-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101296613 Medline TA: Hippokratia Country: Greece |
Other Details:
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Languages: eng Pagination: 98-104 Citation Subset: - |
Affiliation:
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Renal Department, St Andrews General State Hospital, Patras, Greece. |
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