Document Detail

Comparison of esophageal motility in patients with solid dysphagia and mixed dysphagia.
MedLine Citation:
PMID:  16633869     Owner:  NLM     Status:  MEDLINE    
It is unclear whether there is any difference in esophageal motor abnormalities between patients complaining of dysphagia for solids or both solids and liquids. The aim of this study was to determine any difference in the manometric findings between patients with dysphagia for solids and those with mixed dysphagia. Manometric tracings were performed in 200 consecutive patients (66 M, 134 F; mean age = 51 years) with nonobstructive dysphagia. Ambulatory pH studies were performed in all patients. Subjects were divided into two groups: patients with solid dysphagia (n = 94, 33 M, 61 F; mean age = 51 years) and those with mixed dysphagia (n = 106, 33 M, 73 F; mean age = 51 years). A normal motility study was the most frequent finding. Achalasia occurred more frequently in patients with mixed dysphagia than in those with solid dysphagia (12% vs. 3%, p < 0.01). Gastroesophageal reflux disease (GERD) was observed in 59% of patients with solid dysphagia compared with 29% of patients with mixed dysphagia (p < 0.02). The most common esophageal motility abnormality is nonspecific esophageal motility disorders. This study has shown that abnormal esophageal motility occurs slightly more in mixed dysphagia than solid dysphagia. The clinical utility of a symptomatic differentiation of patients with solid or mixed dysphagia appears to be limited.
Chien-Lin Chen; William C Orr
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Dysphagia     Volume:  20     ISSN:  0179-051X     ISO Abbreviation:  Dysphagia     Publication Date:  2005  
Date Detail:
Created Date:  2006-04-24     Completed Date:  2006-05-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8610856     Medline TA:  Dysphagia     Country:  United States    
Other Details:
Languages:  eng     Pagination:  261-5     Citation Subset:  IM    
Department of Medicine, Buddhist Tzu Chi General Hospital and University School of Medicine, Hualien, Taiwan.
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MeSH Terms
Case-Control Studies
Cohort Studies
Deglutition Disorders / etiology*,  physiopathology*
Diagnosis, Differential
Esophageal Motility Disorders / complications,  diagnosis
Follow-Up Studies
Gastroesophageal Reflux / diagnosis,  epidemiology
Hydrogen-Ion Concentration
Manometry / methods
Middle Aged
Reference Values
Risk Assessment
Severity of Illness Index

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