Document Detail

Comparison of endotracheal and peripheral intravenous adrenaline in cardiac arrest. Is the endotracheal route reliable?
MedLine Citation:
PMID:  2882234     Owner:  NLM     Status:  MEDLINE    
Twelve patients presenting to an accident and emergency department in asystolic cardiac arrest were randomly allocated to treatment with endotracheal adrenaline (five patients) or peripheral intravenous adrenaline (seven patients). Femoral-artery blood samples were taken for assay of adrenaline and noradrenaline. After intravenous adrenaline there was a good clinical and biochemical response, but after endotracheal adrenaline there was no change in serum adrenaline and no measurable clinical response. The endotracheal route of adrenaline administration is not reliable in out-of-hospital cardiac arrest.
D N Quinton; G O'Byrne; A R Aitkenhead
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Lancet     Volume:  1     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1987 Apr 
Date Detail:
Created Date:  1987-05-18     Completed Date:  1987-05-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  828-9     Citation Subset:  AIM; IM    
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MeSH Terms
Clinical Trials as Topic
Epinephrine / administration & dosage*,  blood
Evaluation Studies as Topic
Heart Arrest / drug therapy*
Injections, Intravenous
Intubation, Intratracheal
Middle Aged
Random Allocation
Time Factors
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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