Document Detail

Comparison of efficacy and side effects of epidural tramadol and morphine in patients undergoing laminectomy: a repeated dose study.
MedLine Citation:
PMID:  11146613     Owner:  NLM     Status:  MEDLINE    
Tramadol acts through multiple mechanisms and has a low risk of post operative respiratory depression. We compared the efficacy of epidural tramadol with that of morphine for postoperative analgesia in these patients. The demographic data and the summed pain intensity difference scores (SPID) were similar in both the groups. The time to first supplementary dose was significantly shorter in the tramadol group compared to the morphine group (p<0.05). No patient in either group suffered respiratory depression.
L N Yaddanapudi; J Wig; B Singh; M K Tewari
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Neurology India     Volume:  48     ISSN:  0028-3886     ISO Abbreviation:  Neurol India     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2001-01-26     Completed Date:  2001-02-15     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0042005     Medline TA:  Neurol India     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  398-400     Citation Subset:  IM    
Department of Anaesthesia, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
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MeSH Terms
Analgesia, Epidural
Analgesics, Opioid / administration & dosage*,  adverse effects*
Intervertebral Disk Displacement / surgery
Middle Aged
Morphine / administration & dosage*,  adverse effects*
Pain, Postoperative / drug therapy
Tramadol / administration & dosage*,  adverse effects*
Reg. No./Substance:
0/Analgesics, Opioid; 27203-92-5/Tramadol; 57-27-2/Morphine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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