Document Detail

Comparison of effects of manual versus ventilator hyperinflation on respiratory compliance and arterial blood gases in patients undergoing mitral valve replacement.
MedLine Citation:
PMID:  20561856     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare the effects of manual hyperinflation (MHI) and ventilator hyperinflation (VHI) delivered to completely sedated and paralyzed patients undergoing mitral valve replacement (MVR) while maintaining minute ventilation.
METHODS: This was a randomized study with a 2-group, pre-test, post-test experimental design. Effects of hyperinflation were studied on static compliance (C(stat)), dynamic compliance (C(dyn)), oxygenation (Pao(2):Fio(2)), partial pressure of carbon dioxide in arterial blood (Paco(2)), and cologarithm of activity of dissolved hydrogen ions in arterial blood (pH). A sample of 30 patients in the immediate postoperative phase of MVR surgery were included in the study.
RESULTS: No significant differences were found between the groups. Significant improvements were found in oxygenation at both 1minute and 20minutes after MHI, but only at 1minute after VHI (P < .05). VHI led to improved C(dyn) (P < .05).
CONCLUSION: In the immediate postoperative phase of MVR, both techniques produced similar effects on respiratory compliance and oxygenation. MHI produced longer lasting improvements in oxygenation than VHI, whereas VHI produced better improvements in dynamic compliance. Paco(2) and pH were maintained by both.
Faizan Ahmed; Aamir Mohammed Shafeeq; Jamal Ali Moiz; Muhammed Abid Geelani
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial     Date:  2010-04-24
Journal Detail:
Title:  Heart & lung : the journal of critical care     Volume:  39     ISSN:  1527-3288     ISO Abbreviation:  Heart Lung     Publication Date:    2010 Sep-Oct
Date Detail:
Created Date:  2010-09-13     Completed Date:  2011-06-16     Revised Date:  2011-06-22    
Medline Journal Info:
Nlm Unique ID:  0330057     Medline TA:  Heart Lung     Country:  United States    
Other Details:
Languages:  eng     Pagination:  437-43     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2010 Elsevier Inc. All rights reserved.
Hamdard University (Jamia Hamdard), New Delhi, India.
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MeSH Terms
Analysis of Variance
Blood Gas Analysis / instrumentation,  methods
Carbon Dioxide / analysis
Heart Valve Prosthesis Implantation / nursing*
Lung Compliance*
Mitral Valve / pathology,  surgery*
Oxygen Consumption
Partial Pressure
Positive-Pressure Respiration
Postoperative Period
Respiration, Artificial / instrumentation,  methods*
Tidal Volume
Time Factors
Reg. No./Substance:
124-38-9/Carbon Dioxide
Comment In:
Heart Lung. 2011 May-Jun;40(3):270-1; author reply 271-2   [PMID:  21545938 ]

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