Document Detail


Comparison of the effectiveness of 2 treatment regimens in patients with isoniazid-resistant tuberculosis.
MedLine Citation:
PMID:  20218123     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We compared the effectiveness of 2 treatment regimens for isoniazid-resistant tuberculosis (TB) in 42 patients attending a TB referral centre in the Islamic Republic of Iran. The patients were divided into 2 treatment groups: 26 received the 6-month standard HRZE treatment and 16 received a modified treatment of RZE for 6 months. There were no significant differences in age or sex of the groups. With the standard method of treatment, 21 (80.8%) patients were cured, 4 (15.4%) resulted in treatment failure, and 1 (3.8%) died. In the modified treatment group, 16 (100%) patients were cured, These differences were not statistically significantly different (P = 0.194).
Authors:
P Tabarsi; P Baghaei; N Hemmati; M Mirsaeidi; M Kazempour; D Mansouri; M R Masjedi
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Eastern Mediterranean health journal = La revue de sant? de la M?diterran?e orientale = al-Majallah al-?i???yah li-sharq al-mutawassi?     Volume:  15     ISSN:  1020-3397     ISO Abbreviation:  East. Mediterr. Health J.     Publication Date:    2009 Nov-Dec
Date Detail:
Created Date:  2010-03-11     Completed Date:  2010-04-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9608387     Medline TA:  East Mediterr Health J     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  1346-50     Citation Subset:  IM    
Affiliation:
Mycobacteriology Research Centre, National Research Institute of Tuberculosis and Lung Disease, Shaheed Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran. tabarsi@nritld.ac.ir
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MeSH Terms
Descriptor/Qualifier:
Antitubercular Agents / therapeutic use*
Chi-Square Distribution
Drug Administration Schedule
Drug Therapy, Combination
Ethambutol / therapeutic use*
Female
Humans
Iran / epidemiology
Isoniazid / therapeutic use*
Male
Microbial Sensitivity Tests
Middle Aged
Pyrazinamide / therapeutic use*
Retrospective Studies
Rifampin / therapeutic use*
Sputum / microbiology
Streptomycin
Treatment Outcome
Tuberculosis, Pulmonary / drug therapy*,  epidemiology,  microbiology
Chemical
Reg. No./Substance:
0/Antitubercular Agents; 13292-46-1/Rifampin; 54-85-3/Isoniazid; 57-92-1/Streptomycin; 74-55-5/Ethambutol; 98-96-4/Pyrazinamide

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