Document Detail


Comparison of the effect of closed versus open endotracheal suction systems on the development of ventilator-associated pneumonia.
MedLine Citation:
PMID:  15350708     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to compare the effect of closed versus open endotracheal suction systems on the development of ventilator-associated pneumonia (VAP). A prospective, randomized, controlled trial was performed in a medical intensive care unit (MICU) of a university hospital in patients who received mechanical ventilation for more than 48 h. Patients were randomized to receive endotracheal suction with either closed catheters (closed suction group; N-41) or single-use catheters (open suction group; N=37). Cultures were taken from the ventilator tubing of 42 patients to determine the rate of colonization. There was no difference between the groups in terms of the frequency of development of VAP, mortality in the MICU, length of MICU stay and duration of mechanical ventilation. Thirteen patients in the open suction group and 16 patients in the closed suction group became colonized (P=0.14). The colonization rates by Acinetobacter spp. and Pseudomonas aeruginosa were more frequent in the closed suction group than in the open suction group (P<0.01 and P=0.04, respectively). In conclusion, closed endotracheal suction resulted in increased colonization rates of ventilator tubing with multi drug-resistant micro-organisms but did not increase the development of VAP and MICU outcome compared with open endotracheal suction.
Authors:
A Topeli; A Harmanci; Y Cetinkaya; S Akdeniz; S Unal
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  The Journal of hospital infection     Volume:  58     ISSN:  0195-6701     ISO Abbreviation:  J. Hosp. Infect.     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-09-07     Completed Date:  2004-11-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8007166     Medline TA:  J Hosp Infect     Country:  England    
Other Details:
Languages:  eng     Pagination:  14-9     Citation Subset:  IM    
Affiliation:
Medical Intensive Care Unit, Department of Internal Medicine, Faculty of Medicine, Hacettepe University, Ankara 06100, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Aged
Female
Hospital Mortality
Humans
Intensive Care Units
Intubation, Intratracheal / methods*
Logistic Models
Male
Multivariate Analysis
Pneumonia, Aspiration / epidemiology,  prevention & control*
Prospective Studies
Respiration, Artificial*
Risk Factors
Suction / instrumentation*
Turkey / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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