| Comparison of dual-source 64-slice adenosine stress CT perfusion with stress-gated SPECT-MPI for evaluation of left ventricular function and volumes. | |
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MedLine Citation:
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PMID: 22222164 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: Evaluation of left ventricular (LV) volumes and ejection fraction (LVEF) represent important components of pharmacologic stress imaging with either myocardial CT perfusion (CTP) or gated single-photon emission CT (SPECT) myocardial perfusion imaging (SPECT-MPI). OBJECTIVES: We compared measurements of left ventricular function and volumes obtained with CTP and SPECT-MPI. METHODS: Forty-seven patients (mean age, 62 ± 11 years; male, n = 39) underwent stress CTP and SPECT-MPI. LVEF (in %), end-systolic volume (ESV; in mL), and end-diastolic volume (EDV; in mL) derived from stress CTP images were compared with SPECT-MPI. RESULTS: Stress CTP was in good agreement with SPECT-MPI for quantification of LVEF (r = 0.91), EDV (r = 0.75), and ESV (r = 0.83; all P < 0.001). The mean LVEF measured by stress CTP (66% ± 17%) was similar to SPECT-MPI (64% ± 15%). Similar values were also derived for mean EDV (123 ± 30 mL vs 120 ± 34 mL) and ESV (44 ± 28 mL vs 51 ± 34 mL) for CTP and SPECT-MPI, respectively. Good agreement was also shown between both techniques for the assessment of regional wall motion with identical wall motion scores in 95.3% of the segments (κ = 0.79). CONCLUSIONS: LVEF and LV volume parameters as determined by dual-source 64-slice adenosine stress CTP show a high correlation with values obtained with stress-gated SPECT-MPI. |
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Authors:
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Shanmugam Uthamalingam; Gagandeep S Gurm; Manavjot S Sidhu; Daniel J Verdini; Yongkasem Vorasettakarnkij; Leif-Christopher Engel; Ron Blankstein; Wilfred S Mamuya; Udo Hoffman; Thomas J Brady; Ricardo C Cury; Brian B Ghoshhajra |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-11-18 |
Journal Detail:
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Title: Journal of cardiovascular computed tomography Volume: - ISSN: 1876-861X ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2012-1-6 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101308347 Medline TA: J Cardiovasc Comput Tomogr Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 Society of Cardiovascular Computed Tomography. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Cardiac MRI/PET/CT Program, Department of Radiology, Massachusetts General Hospital, Harvard Medical School 165 Cambridge Street, Suite 400, Boston, MA 02114, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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