Document Detail

Comparison of dual-energy X-ray absorptiometry to four other methods to determine body composition in underweight patients with chronic gastrointestinal disease.
MedLine Citation:
PMID:  10726915     Owner:  NLM     Status:  MEDLINE    
Assessment of body composition may provide important information about the nutritional status. The applicability of two safe and convenient methods for body composition analysis, bioelectrical impedance analysis (BIA) and dual-energy x-ray absorptiometry (DXA), in underweight patients with chronic gastrointestinal disease has been sparsely elucidated. Our objective was to compare measurements by DXA with four other methods. Furthermore, we compared total body water (TBW) by BIA using three different BIA equations with measurement of TBW by tritium dilution (TBW-3H2O). Nineteen clinically stable underweight patients with chronic gastrointestinal disease were included in the study (body mass index [BMI], 19.3 +/- 1.2 kg/m2). Body composition was assessed using total body potassium (TBK), isotope dilution of tritium (3H2O), anthropometry (skinfold thickness [SF]), BIA, and DXA. Fat-free mass (FFM) by DXA was in reasonable agreement with body composition measurements by TBK (mean difference(TBK-DXA) = -1.61 kg, r = .88, standard error of the estimate [SEE] = 4.66 kg) and 3H2O (mean difference(3H2O-DXA) = 0.98 kg, r = .93, SEE = 3.34 kg). Although mean values for FFM by DXA differed significantly versus BIA and SF, we found highly significant correlations between the measurements (r = .97 and r = .97, respectively). The mean TBW by BIA was overestimated by 1.9 and 3.1 L compared with TBW-3H2O when prediction equations for normal-weight subjects were used. We conclude that the DXA method is a valuable addition to the list of methods available for body composition studies in clinically stable underweight patients. Our data show that BIA equations for normal-weight subjects overestimated TBW in the patients studied.
K V Haderslev; M Staun
Related Documents :
6441765 - Lithium and lecithin treatment in alzheimer's disease: a pilot study.
6781085 - The therapeutic advantages of a balanced nutritional support system.
6225405 - Effects of antidepressant treatments on dopamine turnover in depressed patients.
14707565 - Early enteral nutrition in mechanically ventilated patients in the prone position.
15466255 - Bone mineral density in lymphangioleiomyomatosis.
23147525 - Impact of antibodies to infliximab on clinical outcomes and serum infliximab levels in ...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Metabolism: clinical and experimental     Volume:  49     ISSN:  0026-0495     ISO Abbreviation:  Metab. Clin. Exp.     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-04-07     Completed Date:  2000-04-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0375267     Medline TA:  Metabolism     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  360-6     Citation Subset:  IM    
Department of Medical Gastroenterology, The Abdominal Center, Rigshospitalet, Copenhagen, Denmark.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Absorptiometry, Photon / methods*
Adipose Tissue / anatomy & histology
Body Composition*
Body Mass Index
Body Water
Body Weight
Chronic Disease
Gastrointestinal Diseases / pathology,  physiopathology*
Regression Analysis
Skinfold Thickness
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Activation of transforming growth factor-beta1 in diabetic kidney disease.
Next Document:  Evidence for impaired glucose effectiveness in cirrhotic patients after liver transplantation.