| Comparison of dose-response curves between acid and pepsin to betazole hydrochloride in the dog with gastric fistula. | |
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MedLine Citation:
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PMID: 789169 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Secretory responses to subcutaneously or intravenously administered betazole hydrochloride of graded doses were compared between acid and pepsin in the dog with gastric fistula. Although the dose related increments in acid and pepsin outputs were parallel in the range of lower doses than 2.0 to 3.0 mg/kg body weight of betazole hydrochloride, higher doses caused in decrease in pepsin output, but did not in acid output. It was pointed out that the dose of betazole hydrochloride that stimulates acid secretion maximally dose not correspond to the maximal stimulation for pepsin secretion in the dog. |
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Authors:
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A Ishimori; H Sakurada; T Kawamura; S Yamagata; Y Miura |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Gastroenterologia Japonica Volume: 10 ISSN: 0435-1339 ISO Abbreviation: Gastroenterol. Jpn. Publication Date: 1975 |
Date Detail:
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Created Date: 1976-12-30 Completed Date: 1976-12-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0152744 Medline TA: Gastroenterol Jpn Country: JAPAN |
Other Details:
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Languages: eng Pagination: 221-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Betazole / administration & dosage* Dogs Dose-Response Relationship, Drug Gastric Fistula Gastric Juice / secretion* Humans Pepsin A / secretion* Pyrazoles / administration & dosage* Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Pyrazoles; 105-20-4/Betazole; EC 3.4.23.1/Pepsin A |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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