Document Detail

Comparison of dobutamine stress echocardiography and stress thallium-201 single-photon emission computed tomography for detecting coronary artery disease.
MedLine Citation:
PMID:  8311966     Owner:  NLM     Status:  MEDLINE    
Dobutamine stress echocardiography and stress thallium-201 single-photon emission computed tomography (SPECT) were compared for detecting coronary artery disease in 120 consecutive patients who underwent concomitant quantitative coronary angiography. The left ventricle was divided into anterior, inferior, and lateral regions. Wall motion or perfusion abnormalities observed within each region were classified as ischemia or fixed abnormality. Both tests showed 81% agreement in all 120 patients. Complete agreement was observed in 77% of the 360 regions analyzed. The overall sensitivity of dobutamine stress echocardiography and thallium-201 SPECT for the detection of coronary artery disease was 85% and 89%, and the specificity was 93% and 85%, respectively. A good correlation was found between the wall motion score index and perfusion defect size at peak stress and at rest (r = 0.70). Dobutamine stress echocardiography and thallium-201 SPECT exhibit a comparable accuracy for diagnosing coronary artery disease, localizing coronary artery stenosis, and detecting regional myocardial abnormalities. The wall motion score index may be useful for evaluating the myocardial area at risk.
M Takeuchi; M Araki; Y Nakashima; A Kuroiwa
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography     Volume:  6     ISSN:  0894-7317     ISO Abbreviation:  J Am Soc Echocardiogr     Publication Date:    1993 Nov-Dec
Date Detail:
Created Date:  1994-03-21     Completed Date:  1994-03-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8801388     Medline TA:  J Am Soc Echocardiogr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  593-602     Citation Subset:  IM    
Second Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
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MeSH Terms
Aged, 80 and over
Coronary Disease / diagnosis*,  radionuclide imaging,  ultrasonography
Dobutamine / diagnostic use*
Middle Aged
Myocardial Ischemia / diagnosis
Predictive Value of Tests
Sensitivity and Specificity
Thallium Radioisotopes / diagnostic use*
Tomography, Emission-Computed, Single-Photon*
Reg. No./Substance:
0/Thallium Radioisotopes; 34368-04-2/Dobutamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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