Document Detail


Comparison of dobutamine electrocardiographic stress test and exercise test in two different groups of patients with unstable angina.
MedLine Citation:
PMID:  9674260     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Exercise testing is a well known means of evaluating patients with unstable angina, but in recent years, alternative methods have been proposed. We prospectively compared standard exercise testing with dobutamine electrocardiographic stress testing for patients who were admitted with a diagnosis of unstable angina. A total of 43 patients were studied, divided into two different groups, according to the presence (group A n = 26) or absence (group B n = 17) of a previous history of coronary artery disease and/or electrocardiographic changes compatible with ischemia on admission. Dobutamine electrocardiographic stress testing was performed in a standard manner at 3 +/- 1 days after admission in group A and at 16 +/- 8 hours after admission in group B. Exercise testing was performed, on average 5 +/- 1 days following the event in group A and 2 days after admission in group B. Agreement between both tests was observed in 39 (91%) cases, Kappa value: 0.81. The dobutamine test predicted the result of the exercise test with a sensitivity of 79% (95% CI 54-90), and a specificity of 100% (95% CI 86-100), with a positive predictive value of 100% and a negative predictive value of 86%. It can be concluded that dobutamine electrocardiographic stress testing is an objective and reliable procedure that accurately predicts the results of standard exercise testing in patients with a diagnosis of unstable angina. If this result were confirmed with a greater number of patients, it would be a good option for definitive diagnosis and risk stratification, in addition to being inexpensive and easy to perform. It can also be particularly useful for patients who cannot perform exercise.
Authors:
J A Martínez Martínez; V E Irazola; R Pérez de la Hoz; P Scagliola; M E Poyatos; E A Sampó
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Medicina     Volume:  57     ISSN:  0025-7680     ISO Abbreviation:  Medicina (B Aires)     Publication Date:  1997  
Date Detail:
Created Date:  1998-09-29     Completed Date:  1998-09-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0204271     Medline TA:  Medicina (B Aires)     Country:  ARGENTINA    
Other Details:
Languages:  eng     Pagination:  397-401     Citation Subset:  IM    
Affiliation:
Division of Coronary Care Unit, Hospital de Clínicas José de San Martín, School of Medicine, University of Buenos Aires, Argentina.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Angina, Unstable / diagnosis*,  physiopathology*
Cardiotonic Agents / diagnostic use*
Dobutamine / diagnostic use*
Electrocardiography / methods*
Exercise Test*
Female
Humans
Male
Middle Aged
Prospective Studies
Chemical
Reg. No./Substance:
0/Cardiotonic Agents; 34368-04-2/Dobutamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Evaluation of hemodynamic and respiratory variables in patients with acute respiratory distress synd...
Next Document:  High frequency ventilation strategies with neonatal conventional ventilator. Assessment of gas excha...