Document Detail

Comparison of diflorasone diacetate and betamethasone dipropionate ointment in the treatment of psoriasis.
MedLine Citation:
PMID:  7073809     Owner:  NLM     Status:  MEDLINE    
In this double-blind study, 100 patients with mild, moderate, or severe thick lesion psoriasis, characterized as acute, subacute, or chronic, were treated with either diflorasone diacetate ointment 0.05% or betamethasone dipropionate ointment 0.05% twice a day for 3 weeks. Clinical evaluations were based on overall improvement and improvement in signs or symptoms of erythema, oedema, lichenification, induration, scaliness, excoriations, pruritus, and soreness. Results showed that both medications were effective and when patients were categorized according to initial lesion severity no statistically significant differences existed between treatment groups.
E Leibsohn
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  The Journal of international medical research     Volume:  10     ISSN:  0300-0605     ISO Abbreviation:  J. Int. Med. Res.     Publication Date:  1982  
Date Detail:
Created Date:  1982-05-21     Completed Date:  1982-05-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0346411     Medline TA:  J Int Med Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  22-7     Citation Subset:  IM    
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MeSH Terms
Administration, Topical
Anti-Inflammatory Agents / therapeutic use*
Betamethasone / analogs & derivatives*,  therapeutic use
Cresols / therapeutic use*
Drug Combinations / therapeutic use
Erythema / drug therapy
Middle Aged
Psoriasis / diagnosis,  drug therapy*
Time Factors
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Cresols; 0/Drug Combinations; 0/Glucocorticoids; 0/Ointments; 33564-31-7/diflorasone diacetate; 378-44-9/Betamethasone; 5593-20-4/betamethasone-17,21-dipropionate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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