| Comparison of diffusion-weighted MR imaging and multidetector-row CT in the detection of liver metastases in patients operated for pancreatic cancer. | |
| | |
MedLine Citation:
|
PMID: 20563868 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
AIM: The purpose of this study is to determine the value of diffusion-weighted MR imaging (DWI) in the detection of liver metastases in patients with pancreatic tumors when compared to multidetector-row CT (MDCT). METHODS: DWI and MDCT were performed in 31 consecutive patients with newly diagnosed, potentially resectable pancreatic tumors. CT images were obtained in the arterial and the portal venous phase. For DWI, a respiratory-triggered single-shot echo-planar imaging sequence (b values: 0, 300, and 600 s/mm(2)) was acquired. Images were analyzed in consensus by two radiologists blinded to the clinical data. Imaging results were correlated with intraoperative surgical and ultrasound findings as well as with results of histopathologic analysis and imaging follow-up. RESULTS: Sensitivity and specificity in detecting liver metastases were 53.3% and 77.8% for MDCT and 86.7% and 97.5% for DWI, respectively. In our study population DWI would have changed the therapeutic management in 4 out of 31 patients (12.9%) when compared to MDCT. CONCLUSION: In the present pilot study, DWI performed significantly better than MDCT in the detection of liver metastases in patients with pancreatic tumors. Therefore, DWI may help to optimize therapeutic management in those patients in the future. |
| | |
Authors:
|
Konstantin Holzapfel; Carolin Reiser-Erkan; Alexander A Fingerle; Merd Erkan; Matthias J Eiber; Ernst J Rummeny; Helmut Friess; Jörg Kleeff; Jochen Gaa |
Related Documents
:
|
15741718 - The diffusion-weighted lesion in acute stroke: heterogeneous patterns of flow/metabolis... 20542568 - Interest of diffusion-weighted and gadolinium-enhanced dynamic mr sequences for the dia... 19394778 - Role of propeller diffusion weighted imaging and apparent diffusion coefficient in the ... 20187198 - Differential diagnosis of mammographically and clinically occult breast lesions on diff... 21951958 - Presenile dementia diagnosed as posterior cortical atrophy. 1922748 - Thickened fatty filum terminale: mr imaging. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Abdominal imaging Volume: 36 ISSN: 1432-0509 ISO Abbreviation: Abdom Imaging Publication Date: 2011 Apr |
Date Detail:
|
Created Date: 2011-04-11 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9303672 Medline TA: Abdom Imaging Country: United States |
Other Details:
|
Languages: eng Pagination: 179-84 Citation Subset: IM |
Affiliation:
|
Department of Radiology, Klinikum Rechts der Isar, Technische Universitaet Muenchen, Ismaninger Str. 22, 81675, Munich, Germany, holzapfel@roe.med.tum.de. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Sequence Polymorphism and Geographical Variation at a Positively Selected MHC-DRB Gene in the Finles...
Next Document: Efficacy of MK-0457 and in combination with vorinostat against Philadelphia chromosome positive acut...