Document Detail


Comparison of different MRI techniques for the assessment of thoracic aortic pathology: 3D contrast enhanced MR angiography, turbo spin echo and balanced steady state free precession.
MedLine Citation:
PMID:  17285264     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: The purpose of this study was to compare two non-contrast 2D techniques with the current contrast-enhanced MRI standard 3D technique for the routine assessment of thoracic aortic pathologies. METHODS: One hundred patients with suspected or known thoracic aortic diseases were examined with a 1.5 T scanner using 2D turbo spin echo (TSE), 2D balanced steady state free precession (balanced SSFP) and 3D contrast-enhanced MR angiography (CE-MRA). The diameters of the aorta at predefined levels were measured. The feasibility to visualize the aortic root and supra-aortic branches was tested. All morphologic abnormalities of the aorta, the aortic wall and the aortic valve, as well as image quality of TSE and balanced SSFP influencing the diagnosis were analysed. RESULTS: Compared to CE-MRA, balanced SSFP and TSE allowed for the detection of a significantly higher number of relevant pathologies (thickened aortic wall and signs of emergency) in less time. No significant differences were found among the sequences for the identification of aneurysms, dissection membranes and thrombi. No single technique was able to address all clinically relevant issues. TSE was associated with a better image quality compared to balanced SSFP, which however did not translate into a significantly improved diagnostic accuracy. CONCLUSION: The total number of pathologic findings was higher using 2D TSE and balanced SSFP when compared to 3D CE-MRA. None of the techniques applied could address all clinically relevant issues. The major drawback of TSE is its relatively long scanning time while balanced SSFP is associated with more artifacts.
Authors:
Rolf Gebker; Osama Gomaa; Bernhard Schnackenburg; Janina Rebakowski; Eckart Fleck; Eike Nagel
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2007-02-07
Journal Detail:
Title:  The international journal of cardiovascular imaging     Volume:  23     ISSN:  1569-5794     ISO Abbreviation:  Int J Cardiovasc Imaging     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-11-02     Completed Date:  2008-02-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100969716     Medline TA:  Int J Cardiovasc Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  747-56     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine - Cardiology, German Heart Institute Berlin, Augustenburger Platz 1, 13353, Berlin, Germany. gebker@dhzb.de
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Analysis of Variance
Aorta, Thoracic*
Aortic Diseases / pathology*
Artifacts
Contrast Media
Female
Humans
Image Interpretation, Computer-Assisted
Imaging, Three-Dimensional
Magnetic Resonance Angiography
Magnetic Resonance Imaging / methods*
Male
Middle Aged
Chemical
Reg. No./Substance:
0/Contrast Media

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