Document Detail

Comparison of corneal sensitivity between FS-LASIK and femtosecond lenticule extraction (ReLEx flex) or small-incision lenticule extraction (ReLEx smile) for myopic eyes.
MedLine Citation:
PMID:  23389552     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: To compare the effect on corneal sensitivity between femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) and femtosecond lenticule extraction (ReLEx flex) or FS-LASIK and small-incision lenticule extraction (ReLEx smile) surgery.
METHODS: Twenty-seven subjects (54 eyes) underwent FS-LASIK, 22 subjects (40 eyes) underwent ReLEx flex, and 32 subjects (61 eyes) underwent ReLEx smile surgery. Cochet-Bonnet esthesiometry (Luneau Ophthalmologie Chartres, Cedex, France) was used to evaluate corneal sensitivity preoperatively as well as at 1 week and 1 and 3 months after surgery.
RESULTS: At 1 week, central, superior, nasal, and temporal corneal sensitivity in the ReLEx flex group was significantly higher than in the FS-LASIK group (P=0.007, 0.004, 0.020, 0.004 respectively) and in the central and inferior areas at 3 months (P=0.002, 0.009 respectively). A higher corneal sensitivity after ReLEx smile surgery was observed in every quadrant at 1 week and 1 and 3 months compared with FS-LASIK surgery (P<0.01). Furthermore, in the ReLEx smile group, there were no statistical differences in the superior and temporal quadrants at 1 month postoperatively compared with preoperatively (5.19 ± 0.61 cm, P=0.198 and 5.64 ± 0.48 cm, P=0.330 respectively) and no significant differences in any quadrant at 3 months.
CONCLUSIONS: Postoperative corneal sensitivity was not remarkably changed after ReLEx smile surgery compared with FS-LASIK. This might be because ReLEx is a flapless procedure.
Shengsheng Wei; Yan Wang
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2013-02-07
Journal Detail:
Title:  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie     Volume:  251     ISSN:  1435-702X     ISO Abbreviation:  Graefes Arch. Clin. Exp. Ophthalmol.     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-05-24     Completed Date:  2013-11-06     Revised Date:  2013-11-07    
Medline Journal Info:
Nlm Unique ID:  8205248     Medline TA:  Graefes Arch Clin Exp Ophthalmol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1645-54     Citation Subset:  IM    
Tianjin Eye Hospital & Eye Institute, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin Medical University, No 4. Gansu Rd, Heping District, Tianjin, 300020, China.
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MeSH Terms
Cornea / physiopathology*
Corneal Pachymetry
Corneal Stroma / surgery*
Keratomileusis, Laser In Situ / methods*
Lasers, Excimer / therapeutic use*
Middle Aged
Myopia / physiopathology,  surgery*
Prospective Studies
Sensation / physiology*
Surgical Flaps
Young Adult
Erratum In:
Graefes Arch Clin Exp Ophthalmol. 2013 Oct;251(10):2495-7

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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