Document Detail


Comparison of contrast-enhanced harmonic ultrasonography and power Doppler ultrasonography for depicting vascularity of hepatocellular carcinoma identified by angiography-assisted CT.
MedLine Citation:
PMID:  14662120     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The sensitivity of contrast-enhanced harmonic gray scale imaging was compared with that of power Doppler sonography in depicting tumor vascularity and contrast enhancement of hepatocellular carcinoma (HCC) identified by angiography-assisted computed tomography (CT). One hundred thirty-nine classic HCC nodules (108 patients), each appearing as a high-attenuation mass on early-phase CT during hepatic arteriography and as a perfusion defect on CT during arterial portography, were evaluated. Vascular findings and contrast enhancement patterns were evaluated by contrast-enhanced harmonic gray scale imaging. Arterial pulsatile flow into each nodule was checked by power Doppler sonography. Sensitivity of each modality for depicting tumor vascularity was examined by angiography-assisted CT findings as the gold standard. The sensitivity of contrast-enhanced harmonic gray scale imaging (134/139, 96.4%) was significantly greater than that of power Doppler sonography (96/139, 69.1%) (P<0.05). Twenty-six of twenty-seven nodules (96.3%) in the lateral segment, in which motion artifact is likely, were enhanced by contrast-enhanced harmonic gray scale imaging. Contrast-enhanced harmonic gray scale imaging is more sensitive than power Doppler sonography and is a noninvasive method that can be used as effectively as angiography-assisted CT to evaluate tumor vessels and contrast enhancement of HCC.
Authors:
Takashi Honda; Takashi Kumada; Seiki Kiriyama; Yasuhiro Sone; Makoto Tanikawa; Yasuhiro Hisanaga; Hidenori Toyoda; Hiroki Ishiguro; Sadanobu Ogawa; Kenji Takeshima; Toshiaki Kawachi; Toshio Hibi; Kazuhiko Hayashi; Yoshiaki Katano; Yoshihide Fukuda; Hidemi Goto
Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Hepatology research : the official journal of the Japan Society of Hepatology     Volume:  27     ISSN:  -     ISO Abbreviation:  Hepatol. Res.     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2003-Dec-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9711801     Medline TA:  Hepatol Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  315-322     Citation Subset:  -    
Affiliation:
Department of Gastroenterology, Ogaki Municipal Hospital, 4-86 Minaminokawa, Ogaki, 503-8502, Gifu, Japan
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