| Comparison of clinical outcomes following guided tissue regeneration treatment with a polylactic acid barrier or a collagen membrane. | |
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MedLine Citation:
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PMID: 20228976 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This prospective, randomized, controlled clinical trial compared the clinical outcomes for a polylactic acid barrier versus a collagen membrane in conjunction with guided tissue regeneration (GTR). Thirty patients with chronic periodontitis and at least one intrabony defect of a minimum 4 mm were enrolled. Following full-mouth scaling, GTR using a collagen membrane or a polylactic acid barrier was performed at one site in each patient. At 1 week before and 6 months after surgery, probing pocket depth (PPD), clinical attachment level (CAL), marginal tissue recession, and bone fill were assessed. A significant reduction in PPD (2.50 +/- 1.35 mm for the polylactic acid barrier and 2.60 +/- 1.08 mm for the collagen membrane) was obtained, in addition to gains in CAL (2.40 +/- 1.17 mm for the polylactic acid barrier and 2.60 +/- 1.26 mm for the collagen membrane) and bone fill (0.33 +/- 1.89 mm for polylactic acid barrier and 2.57 +/- 1.64 mm for collagen membrane), for each group compared to baseline. Significantly, the results from 6 months after surgery showed that there was greater bone fill when the collagen membrane was used compared to the polylactic acid barrier. |
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Authors:
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Shih-Yun Wu; Yen-Ting Chen; Chi-Wei Chen; Lin-Yang Chi; Nai-Ying Hsu; Shan-Ling Hung; Li-Jane Ling |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The International journal of periodontics & restorative dentistry Volume: 30 ISSN: 0198-7569 ISO Abbreviation: Int J Periodontics Restorative Dent Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-15 Completed Date: 2010-05-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8200894 Medline TA: Int J Periodontics Restorative Dent Country: United States |
Other Details:
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Languages: eng Pagination: 173-9 Citation Subset: D |
Affiliation:
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Department of Periodontics, Taipei Veterans General Hospital, Taiwan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Absorbable Implants Adult Alveolar Bone Loss / surgery* Analysis of Variance Bone Regeneration* Chronic Periodontitis / surgery Collagen Female Guided Tissue Regeneration, Periodontal / methods* Humans Lactic Acid Male Membranes, Artificial* Middle Aged Periodontal Index Polymers Prospective Studies Statistics, Nonparametric |
| Chemical | |
Reg. No./Substance:
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0/Membranes, Artificial; 0/Polymers; 26100-51-6/poly(lactic acid); 50-21-5/Lactic Acid; 9007-34-5/Collagen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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