| Comparison of cimetidine and tripotassium dicitrato bismuthate in healing and relapse of duodenal ulcers. | |
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MedLine Citation:
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PMID: 6360774 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A comparison between cimetidine and tripotassium dicitrato bismuthate liquid (TDB) in the treatment of endoscopically diagnosed duodenal ulcer by single-blind randomized trial in 48 patients has shown 18 (75%) out of 24 patients receiving TDB and 13 (54%) out of 24 patients receiving cimetidine healed after 4 weeks' therapy. Symptomatic improvement within 1 month was seen in 19 patients on TDB and 18 patients on cimetidine, but did not only occur in patients whose ulcers healed. On follow-up, endoscopically proven relapse occurred within 1 year in 47% of patients whose ulcers had healed during treatment with TDB in comparison with 60% of those healing on cimetidine. |
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Authors:
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D R Shreeve; H J Klass; P E Jones |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Digestion Volume: 28 ISSN: 0012-2823 ISO Abbreviation: Digestion Publication Date: 1983 |
Date Detail:
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Created Date: 1984-02-14 Completed Date: 1984-02-14 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0150472 Medline TA: Digestion Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 96-101 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Age Factors Aged Bismuth / therapeutic use* Cimetidine / therapeutic use* Clinical Trials as Topic Duodenal Ulcer / diagnosis, drug therapy*, prevention & control Duodenoscopy Female Follow-Up Studies Humans Male Middle Aged Organometallic Compounds* Random Allocation Recurrence Time Factors Wound Healing / drug effects |
| Chemical | |
Reg. No./Substance:
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0/Organometallic Compounds; 51481-61-9/Cimetidine; 57644-54-9/bismuth tripotassium dicitrate; 7440-69-9/Bismuth |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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