Document Detail

Comparison of cimetidine and tripotassium dicitrato bismuthate in healing and relapse of duodenal ulcers.
MedLine Citation:
PMID:  6360774     Owner:  NLM     Status:  MEDLINE    
A comparison between cimetidine and tripotassium dicitrato bismuthate liquid (TDB) in the treatment of endoscopically diagnosed duodenal ulcer by single-blind randomized trial in 48 patients has shown 18 (75%) out of 24 patients receiving TDB and 13 (54%) out of 24 patients receiving cimetidine healed after 4 weeks' therapy. Symptomatic improvement within 1 month was seen in 19 patients on TDB and 18 patients on cimetidine, but did not only occur in patients whose ulcers healed. On follow-up, endoscopically proven relapse occurred within 1 year in 47% of patients whose ulcers had healed during treatment with TDB in comparison with 60% of those healing on cimetidine.
D R Shreeve; H J Klass; P E Jones
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Digestion     Volume:  28     ISSN:  0012-2823     ISO Abbreviation:  Digestion     Publication Date:  1983  
Date Detail:
Created Date:  1984-02-14     Completed Date:  1984-02-14     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0150472     Medline TA:  Digestion     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  96-101     Citation Subset:  IM    
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MeSH Terms
Age Factors
Bismuth / therapeutic use*
Cimetidine / therapeutic use*
Clinical Trials as Topic
Duodenal Ulcer / diagnosis,  drug therapy*,  prevention & control
Follow-Up Studies
Middle Aged
Organometallic Compounds*
Random Allocation
Time Factors
Wound Healing / drug effects
Reg. No./Substance:
0/Organometallic Compounds; 51481-61-9/Cimetidine; 57644-54-9/bismuth tripotassium dicitrate; 7440-69-9/Bismuth

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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