Document Detail

Comparison of chlormethiazole (Heminevrin) and chlordiazepoxide (Librium) in the treatment of acute alcohol withdrawal.
MedLine Citation:
PMID:  6674819     Owner:  NLM     Status:  MEDLINE    
This study was carried out to compare the efficacy of chlormethiazole and chlordiazepoxide in the treatment of acute alcohol withdrawal syndrome in 40 patients. Repeated biochemical, clinical, and psychophysiological measurements were obtained in a randomized, double-blind design in which one group of patients received chlormethiazole and a second group received chlordiazepoxide over a period of 7 days. Analysis indicated both drugs to be of equivalent potency and were equally well tolerated by patients. The more severe aspects of withdrawal were brought under control within the first 4 days of treatment. However, even at 7 days, there still persisted some symptoms attributable to the withdrawal from alcohol.
Y D Lapierre; D R Bulmer; L K Oyewumi; M L Mauguin; V J Knott
Related Documents :
23517109 - High single-session success rate of endoscopic bilateral stent-in-stent placement with ...
19717249 - Long-term outcomes of office-based buprenorphine/naloxone maintenance therapy.
23557789 - Bone mineral density 5 years after parathyroidectomy in hemodialysis patients with seco...
23977919 - Nerve sheath catheter analgesia for forequarter amputation in paediatric oncology patie...
18552489 - Long-term outcomes of treatment-resistant heroin addicts with and without dsm-iv axis i...
22677329 - Maxillary advancement with conventional orthognathic surgery in patients with cleft lip...
10149559 - Clinical and radiographic results with the trilock femoral component--a wedge-fit porou...
24750379 - Do nonsteroidal anti-inflammatory drugs affect the outcome of arthroscopic bankart repair?
9926809 - Comparison of laparoscopic versus open repair of paraesophageal hernia.
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Neuropsychobiology     Volume:  10     ISSN:  0302-282X     ISO Abbreviation:  Neuropsychobiology     Publication Date:  1983  
Date Detail:
Created Date:  1984-06-20     Completed Date:  1984-06-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7512895     Medline TA:  Neuropsychobiology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  127-30     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Alcohol Withdrawal Delirium / drug therapy*
Alcoholism / rehabilitation*
Chlordiazepoxide / adverse effects,  therapeutic use*
Chlormethiazole / adverse effects,  therapeutic use*
Double-Blind Method
Middle Aged
Psychoses, Alcoholic / drug therapy*
Reg. No./Substance:
533-45-9/Chlormethiazole; 58-25-3/Chlordiazepoxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  High plasma concentrations of metoclopramide are not detected by radioreceptor assay.
Next Document:  Depression-inducing and antidepressive effects of neuroleptics. Experiences with flupenthixol and fl...