| Comparison of changes in markers of muscle damage induced by eccentric exercise and ischemia/reperfusion. | |
| | |
MedLine Citation:
|
PMID: 19804580 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
To examine the effects of eccentric exercise (EE) and ischemia/reperfusion (I/R) on the markers of muscle damage, 72 rats were randomly assigned to the EE group, I/R group and control group (C), respectively. The rats in EE ran downhill on a treadmill with a 16 ° inclination at a constant speed for 90 min, and the rats in the I/R group underwent 90 min of four-limb ischemia, followed by 24, 48 and 72 h of reperfusion. Blood and tissue samples were collected immediately, 24, 48 and 72 h after exercise or reperfusion. Quantitative analyses showed that the I/R group had a significantly larger mitochondrial volume at 24 h after reperfusion compared with the C, and there were more disrupted Z-lines in the EE group and more disrupted mitochondria in the I/R group at 24 h after exercise or reperfusion. When compared with the C, a significantly lower total antioxidant capacity and higher interleukin-6 value were observed after exercise or reperfusion. Our data suggest that although EE and I/R result in some similar changes in the muscle damage markers, there are still some differences. The EE- and I/R-induced muscle damage may be due to different mechanisms. |
| | |
Authors:
|
Q-S Su; J-G Zhang; R Dong; B Hua; J-Z Sun |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Scandinavian journal of medicine & science in sports Volume: 20 ISSN: 1600-0838 ISO Abbreviation: Scand J Med Sci Sports Publication Date: 2010 Oct |
Date Detail:
|
Created Date: 2010-11-18 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9111504 Medline TA: Scand J Med Sci Sports Country: Denmark |
Other Details:
|
Languages: eng Pagination: 748-56 Citation Subset: IM |
Copyright Information:
|
© 2009 John Wiley & Sons A/S. |
Affiliation:
|
Faculty of Sports Medicine, Chengdu Sports University, Chengdu, China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The role of systemic inflammation in age-related muscle weakness and wasting.
Next Document: Maximal strength training improves walking performance in peripheral arterial disease patients.