Document Detail

Comparison of cerebrospinal fluid pressure in propofol- and thiopental-anesthetized eucapnic dogs.
MedLine Citation:
PMID:  8511849     Owner:  NLM     Status:  MEDLINE    
Cerebrospinal fluid pressure (CSFp) was measured as part of the neurologic assessment of dogs with suspected intracranial disease. Because propofol has not been shown to cause an increase in intracranial pressure in humans, the authors examined its effect on (CSFp) in dogs to determine if it would be an appropriate substitute for thiopental as an anesthetic agent for the measurement of CSFp. The CSF pressure in eucapnic propofol-anesthetized dogs (105 +/- 5.6 mm H2O) was not significantly different (p < .05) from CSFp in eucapnic thiopental-anesthetized dogs (103.8 +/- 6.6 mm H2O).
T L Wooten; C T Lowrie
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Veterinary surgery : VS     Volume:  22     ISSN:  0161-3499     ISO Abbreviation:  Vet Surg     Publication Date:    1993 Mar-Apr
Date Detail:
Created Date:  1993-07-12     Completed Date:  1993-07-12     Revised Date:  2011-04-25    
Medline Journal Info:
Nlm Unique ID:  8113214     Medline TA:  Vet Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  148-50     Citation Subset:  IM    
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing 48824.
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MeSH Terms
Anesthesia, Intravenous / veterinary*
Carbon Dioxide / blood
Cerebrospinal Fluid Pressure / drug effects*
Dogs / blood,  cerebrospinal fluid*,  surgery
Propofol / pharmacology*
Thiopental / pharmacology*
Reg. No./Substance:
124-38-9/Carbon Dioxide; 2078-54-8/Propofol; 76-75-5/Thiopental

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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