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Comparison of central venous catheter and peripheral vein samples of antibiotics in children with cystic fibrosis.
MedLine Citation:
PMID:  23289453     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
PURPOSE.: To determine if accurate serum antibiotic levels can be obtained from central venous catheters (CVCs) in pediatric patients with cystic fibrosis. DESIGN AND METHODS.: Fifty paired CVC-peripheral vancomycin or tobramycin specimens were collected within 5 min of each other following a 5-ml flush and discard. Specimen samples were randomized by first site drawn. RESULTS.: CVC-peripheral antibiotic levels were highly correlated (r =.97, p <.001), with no statistically significant difference (t = 1.18, p =.25). Bland-Altman plot analysis revealed a bias of.47, with limits of agreement ranging from -4.20 to 6.87. PRACTICE IMPLICATIONS.: Accurate antibiotic concentrations can be obtained from CVCs, reducing pediatric patient trauma and stress.
Authors:
Karen Wilson; Patricia A Jamerson
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Publication Detail:
Type:  Journal Article     Date:  2012-11-27
Journal Detail:
Title:  Journal for specialists in pediatric nursing : JSPN     Volume:  18     ISSN:  1744-6155     ISO Abbreviation:  J Spec Pediatr Nurs     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101142025     Medline TA:  J Spec Pediatr Nurs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  33-41     Citation Subset:  IM; N    
Copyright Information:
© 2012, Wiley Periodicals, Inc.
Affiliation:
Department of Pediatrics, Washington University.
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