| Comparison of central corneal thickness using optical low-coherence reflectometry and spectral-domain optical coherence tomography. | |
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MedLine Citation:
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PMID: 22436868 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE: To assess intraobserver and interobserver reliability of central corneal thickness (CCT) measurements using optical low-coherence reflectometry (OLCR) technology and its agreement with spectral-domain optical coherence tomography (SD-OCT). SETTING: Rio Hortega University Hospital, Valladolid, Spain. DESIGN: Evaluation of diagnostic technology. METHODS: To analyze OLCR intraobserver repeatability, 1 examiner obtained 4 successive measurements. To study interobserver reproducibility, a different examiner obtained another CCT measurement. To determine agreement with SD-OCT, the first examiner also obtained CCTs. Intraobserver and interobserver within-subject standard deviation (S(w)), coefficient of variation (CV(w)), and limits of agreement (LoA) were obtained for OLCR reliability analysis; for study agreement, data were analyzed using the paired-sample t test and the LoA were calculated. RESULTS: For OLCR intraobserver repeatability, the S(w) and precision (1.96×S(w)) were 2.33 and 4.56 μm, respectively. The intraobserver CV(w) was 0.42%. For interobserver reproducibility, the S(w) and precision were 11.59 and 22.71 μm, respectively; the CV(w) was 2.10%. The mean difference between observers was -1.35 μm (95% confidence interval [CI], -3.97 to 1.26). The width of the LoA was 45.27 μm. The mean CCT difference between OLCR and SD-OCT was 5.68±11.46 μm (95% CI, 8.29-3.08 μm; P=.0001), and the width of the LoA was 44.93 μm. CONCLUSIONS: Optical low-coherence reflectometry technology provided reliable intraobserver and interobserver CCT measurements. Although OLCR underestimated the pachymetry by less than 6 μm compared with SD-OCT, its interchangeability fell within the range of interobserver reproducibility. Both noncontact pachymetry measurements seem to be clinically useful and may be used interchangeably with minimum calibration adjustment. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned. |
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Authors:
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Alberto López-Miguel; María Encarnación Correa-Pérez; Silvia Miranda-Anta; Darío Iglesias-Cortiñas; María Begoña Coco-Martín; Miguel J Maldonado |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-3-19 |
Journal Detail:
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Title: Journal of cataract and refractive surgery Volume: - ISSN: 1873-4502 ISO Abbreviation: - Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-3-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8604171 Medline TA: J Cataract Refract Surg Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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From the Institute of Applied Ophthalmobiology (López-Miguel, Coco-Martín, Maldonado), University of Valladolid; Visión I+D, SL (López-Miguel), and Rio Hortega University Hospital (Correa, Miranda-Anta, Iglesias-Cortiñas), Valladolid, Spain. |
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