| Comparison of the causes of late death following aortic and mitral valve replacement. VA Co-operative Study on Valvular Heart Disease. | |
| | |
MedLine Citation:
|
PMID: 8162209 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This report examines and compares the causes of late non-surgical death in 146 of 690 (21%) patients undergoing isolated aortic valve replacement (AVR) and in 79 of 273 (29%) patients undergoing mitral valve replacement (MVR) over a five year follow up period. The distribution of valve related, cardiac but not valve-related and non-cardiac deaths was 43%, 23% and 34% respectively for AVR and 65%, 29% and 6% respectively for MVR; the difference between these distributions was statistically significant. The specific causes of valve related deaths included bleeding (11% vs. 5% for MVR vs. AVR), systemic embolization (6% vs. 4% for MVR vs. AVR), endocarditis (14% vs. 8% for MVR vs. AVR), valve regurgitation (8% vs. 5% for MVR vs. AVR) and valve obstruction (3% vs. 5% for MVR vs. AVR). Sudden death (less than one hour from the onset of acute symptoms) accounted for 23% of deaths for MVR and 16% for AVR. The deaths due to congestive heart failure with normal prosthetic valve function were 13% and 8% for MVR and AVR respectively. Non-cardiac causes accounted for only 6% of MVR deaths but 34% of AVR deaths (p < 0.001). There was no significant difference in the late mortality between mechanical and bioprosthetic valves in the aortic position (24% vs. 22%), but the cumulative rate of late deaths was higher in patients with the Björk-Shiley than with the Hancock valve in the mitral position (41% vs. 25%, p < 0.02). In conclusion, about one quarter of patients surviving either aortic or mitral valve replacement died within five years.(ABSTRACT TRUNCATED AT 250 WORDS) |
| | |
Authors:
|
M H Hwang; C M Burchfiel; G K Sethi; C Oprian; F L Grover; W G Henderson; K Hammermeister |
Related Documents
:
|
18627019 - Tissue engineering lamb heart valve leaflets. 3884479 - The demonstration of cardiac pathology using perfusion-fixation. 7422859 - Thrombosis of björk-shiley aortic valve prostheses. 23733649 - Pulmonary vascular stiffness: measurement, modeling, and implications in normal and hyp... 23660569 - Diagnostic value of color doppler ultrasonography and mdct angiography in complications... 8901729 - Predictive value of prosthetic valve area index for early and late clinical results aft... 1616159 - Halothane relaxes previously constricted human epicardial coronary artery segments more... 9194449 - Transient obstruction of the internal carotid artery during angiography. 21427089 - Changes in low right atrial conduction times during pulmonary vein isolation for atrial... |
Publication Detail:
|
Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
|
Title: The Journal of heart valve disease Volume: 3 ISSN: 0966-8519 ISO Abbreviation: J. Heart Valve Dis. Publication Date: 1994 Jan |
Date Detail:
|
Created Date: 1994-05-20 Completed Date: 1994-05-20 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9312096 Medline TA: J Heart Valve Dis Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 17-24 Citation Subset: IM |
Affiliation:
|
VA Hospital, Hines, IL. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aortic Valve / surgery Cause of Death* Death, Sudden / epidemiology Heart Valve Diseases / mortality, surgery Heart Valve Prosthesis / mortality* Humans Middle Aged Mitral Valve / surgery Prospective Studies Survival Rate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Retrograde strut embolization in a fractured Björk-Shiley mitral prosthesis.
Next Document: The tricuspid valve is bicuspid.