Document Detail

Comparison of caudal bupivacaine and bupivacaine-tramadol for postoperative analgesia in children undergoing hypospadias surgery.
MedLine Citation:
PMID:  19889260     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare the effectiveness of caudal bupivacaine and bupivacaine-tramadol for postoperative analgesia in children undergoing hypospadias surgery. STUDY DESIGN: Quasi experimental study. PLACE AND DURATION OF STUDY: The Postgraduate Medical Institute, Hayatabad Medical Complex, Peshawar, from February 2006 to August 2007. METHODOLOGY: The study was conducted on 60 male children undergoing elective hypospadias surgery at the study centre. Patients were divided into two groups of 30 each. Patients in group 'B' (bupivacaine) were given 0.5 ml/kg of 0.25% plain bupivacaine, while patients in group 'BT' (bupivacaine and tramadol) were given 0.5 ml/kg of 0.25% bupivacaine in combination with 1 mg/kg of tramadol in caudal epidural space just after induction of anaesthesia. ASA status, duration of anaesthesia,duration of surgery, type of anaesthesia and maintenance of anaesthesia were similar for both groups. In the recovery room, patients were compared for pain scores, sedation score, need for rescue analgesia and any unwanted side effects for 24 hours postoperatively. All patients were assessed haemodynamically at regular intervals intraoperatively in both groups. A t-test was used to compare the mean values of the group with significance at p < 0.05. RESULTS: Mean age of the children was 4.2+/-2.35 and 5.5+/-1.51 years in group B and BT respectively. Their weight ranged from 10-30 kg. A lower pain score was observed in the bupivacaine-tramadol group during the first 24 hours in the recovery room, as well as in the postoperative ward. The mean duration of analgesia was significantly prolonged and the requirement for rescue analgesics were significantly less in the bupivacaine-tramadol group (p < 0.0001) postoperatively. Demographic data, haemodynamic variables, sedation score, and minor complications were not significantly different in the two groups. CONCLUSION: Caudal tramadol with bupivacaine provides prolonged and good quality postoperative analgesia compared to plain bupivacaine in children undergoing hypospadias surgery.
Nasreen Laiq; Mohammad Naeem Khan; Tahmeedullah; Yousuf Khan Gandapur; Shahid Khan
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of the College of Physicians and Surgeons--Pakistan : JCPSP     Volume:  19     ISSN:  1022-386X     ISO Abbreviation:  J Coll Physicians Surg Pak     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-11-05     Completed Date:  2010-01-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9606447     Medline TA:  J Coll Physicians Surg Pak     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  678-81     Citation Subset:  IM    
Department of Anaesthesiology, PGMI/Hayatabad Medical Complex, No. 156 Street No. 3, Hayatabad, Peshawar.
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MeSH Terms
Analgesics, Opioid / administration & dosage*
Anesthesia, Caudal
Bupivacaine / administration & dosage*
Child, Preschool
Hypospadias / surgery*
Pain Measurement
Pain, Postoperative / prevention & control
Tramadol / administration & dosage*
Reg. No./Substance:
0/Analgesics, Opioid; 2180-92-9/Bupivacaine; 27203-92-5/Tramadol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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