Document Detail

Comparison between peak expiratory flow rate and forced expiratory volume in one second in the evaluation of children suspected to have asthma.
MedLine Citation:
PMID:  17301387     Owner:  NLM     Status:  In-Data-Review    
This study was conducted to evaluate whether forced expiratory volume in 1 second (FEV1) for the diagnosis of bronchial reactivity by means of the free-running exercise test and bronchodilator inhalation, could be appropriately replaced by simple measurements of peak expiratory flow rate (PEFR) in children.We studied 108 referred symptomatic children (due to chronic cough or wheezing) suspected to have asthma aged 5-14y. Forced breathing spirometry and the "Mini-Wright peak flow meter" tests were recorded before and fifteen minutes after the challenge with free- running exercise or bronchodilator (Salbutamol) inhalation, regarding the baseline FEV1 value (FEV1> 80% considered as normal).There was a high correlation between PEFR and FEV1 (in absolute value and percent predicted) measured before and after bronchodilator inhalation test (r = 0.48, P = 0.05) in comparison to the values referred to free- running exercise test (r = 0.26, P = 0.01)."forced breathing spirometry" and "Mini-Wright peak flow" cannot be used interchangeably for diagnosing asthma, and PEFR measurement should remain a procedure for monitoring and following up the patients.
Mohammad Gharagozlou; Farshid Kompani; Masoud Movahedi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Iranian journal of allergy, asthma, and immunology     Volume:  3     ISSN:  1735-1502     ISO Abbreviation:  Iran J Allergy Asthma Immunol     Publication Date:  2004 Mar 
Date Detail:
Created Date:  2007-02-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101146178     Medline TA:  Iran J Allergy Asthma Immunol     Country:  Iran    
Other Details:
Languages:  eng     Pagination:  21-4     Citation Subset:  -    
Department of the Immunology and Allergy, The Children’s Medical Center Hospital, Tehran University of Medical Sciences, Tehran, Iran.
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