Document Detail

Comparison between immunofixation and crossed immunoelectrophoresis for the detection of C3 activation products.
MedLine Citation:
PMID:  498518     Owner:  NLM     Status:  MEDLINE    
C3 breakdown products were measured in 51 fresh and stored sera and/or EDTA plasma samples from 18 healthy subjects, 8 patients affected by essential mixed cryoglobulinaemia, and 15 patients with miscellaneous glomerulonephritis, by simultaneous crossed immunoelectrophoresis and immunofixation. C3 splitting products, as determined by both methods compared well, and showed a highly significant correlation. The advantages and reliability of these two methods are discussed. Immunofixation seems to be the most suitable for routine use in clinical practice, being less expensive and more rapid to perform.
A De Vecchi; G Montagnino; L Massaro; A Constantino; P L Bencini; A Tarantino
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Clinica chimica acta; international journal of clinical chemistry     Volume:  97     ISSN:  0009-8981     ISO Abbreviation:  Clin. Chim. Acta     Publication Date:  1979 Sep 
Date Detail:
Created Date:  1980-01-24     Completed Date:  1980-01-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1302422     Medline TA:  Clin Chim Acta     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  27-32     Citation Subset:  IM    
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MeSH Terms
Complement C3 / analysis*
Glomerulonephritis / diagnosis
Immunoelectrophoresis / methods*
Immunoelectrophoresis, Two-Dimensional / methods*
Paraproteinemias / immunology
Reg. No./Substance:
0/Complement C3; 0/Cryoglobulins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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