Document Detail

Comparison between carotid-femoral and brachial-ankle pulse wave velocity as measures of arterial stiffness.
MedLine Citation:
PMID:  19550355     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Arterial stiffness is an important risk factor for cardiovascular disease. Carotid-femoral pulse wave velocity (cfPWV) is the most recognized and established index of arterial stiffness. An emerging automatic measure of PWV primarily used in the Asian countries is brachial-ankle PWV (baPWV). METHOD: To systematically compare these two methodologies, we conducted a multicenter study involving a total of 2287 patients. RESULTS: There was a significant positive relation between baPWV and cfPWV (r = 0.73). Average baPWV was approximately 20% higher than cfPWV. Both cfPWV and baPWV were significantly and positively associated with age (r = 0.56 and 0.64), systolic blood pressure (r = 0.49 and 0.61), and the Framingham risk score (r = 0.48 and 0.63). The areas under the receiver operating curves (ROCs) of PWV to predict the presence of both stroke and coronary artery disease were comparable between cfPWV and baPWV. CONCLUSION: Collectively, these results indicate that cfPWV and baPWV are indices of arterial stiffness that exhibit similar extent of associations with cardiovascular disease risk factors and clinical events.
Hirofumi Tanaka; Masanori Munakata; Yuhei Kawano; Mitsuru Ohishi; Tetsuo Shoji; Jun Sugawara; Hirofumi Tomiyama; Akira Yamashina; Hisayo Yasuda; Toshitami Sawayama; Toshio Ozawa
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study    
Journal Detail:
Title:  Journal of hypertension     Volume:  27     ISSN:  1473-5598     ISO Abbreviation:  J. Hypertens.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-11-09     Completed Date:  2010-01-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8306882     Medline TA:  J Hypertens     Country:  England    
Other Details:
Languages:  eng     Pagination:  2022-7     Citation Subset:  IM    
Department of Kinesiology and Health Education, The University of Texas at Austin, Austin, TX 78712, USA.
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MeSH Terms
Aged, 80 and over
Ankle Brachial Index*
Blood Flow Velocity / physiology*
Carotid Arteries / physiology*
Coronary Artery Disease / diagnosis,  epidemiology,  physiopathology
Femoral Artery / physiology*
Hypertension / diagnosis,  epidemiology,  physiopathology*
Japan / epidemiology
Middle Aged
Pulsatile Flow / physiology*
ROC Curve
Risk Factors
United States / epidemiology
Young Adult
Comment In:
J Hypertens. 2009 Oct;27(10):1960-1   [PMID:  19893429 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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