Document Detail


Comparison between 64-row CT angiography and digital subtraction angiography in the study of lower extremities: personal experience.
MedLine Citation:
PMID:  19774439     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: This study was undertaken to evaluate the potential of 64-row multislice computed tomography (CT) versus digital subtraction angiography (DSA) in detecting significant lesions of lower-extremity inflow and runoff arteries. MATERIALS AND METHODS: Fifty-three patients underwent 64-row multislice CT and DSA over a mean of 36 days. The vascular tree was divided into 33 segments. Three readers independently reviewed the axial CT scans and multiplanar oblique and two- and three-dimensional reconstructions (maximum intensity projection and volume rendering) images to assess degree of stenosis according to four categories: 1 (0%-49% stenosis); 2 (50%-99% stenosis); 3 (occluded); 4 (not evaluable). In all cases, DSA was performed by arterial catheterisation. RESULTS: In 53 patients, 1,440 segments were evaluated (infrarenal aorta and 16 arterial segments for each leg; 42 bilateral studies, 11 unilateral studies). Compared with DSA, CT angiography yielded 97.2% sensitivity, 97% specificity, 92.5% positive predictive value, 98.9% negative predictive value, 97.1% diagnostic accuracy and 95.4% concordance on the degree of stenosis. CONCLUSIONS: Sixty-four-row multislice CT proved to be helpful in detecting haemodynamically significant lesions in peripheral arterial occlusive disease and improved the results obtained with 4- and 16-slice multidetector CT. In addition, owing to the high spatial resolution and rigorous technique, no variations in the data obtained below the knee were detected, overcoming a limitation of earlier generations of CT scanners.
Authors:
S Cernic; F Pozzi Mucelli; A Pellegrin; R Pizzolato; M A Cova
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2009-09-22
Journal Detail:
Title:  La Radiologia medica     Volume:  114     ISSN:  1826-6983     ISO Abbreviation:  Radiol Med     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2010-01-21     Completed Date:  2010-02-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0177625     Medline TA:  Radiol Med     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  1115-29     Citation Subset:  IM    
Affiliation:
Unit? Clinico Operativa di Radiologia, Universit? degli Studi di Trieste, Ospedale di Cattinara, Strada di Fiume 447, 34149, Trieste, Italy. stefanocernic@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Angiography / methods*
Angiography, Digital Subtraction / methods*
Female
Humans
Image Processing, Computer-Assisted
Knee / radiography
Leg / radiography
Lower Extremity / blood supply,  radiography*
Male
Middle Aged
Peripheral Vascular Diseases / radiography*
Predictive Value of Tests
Radiographic Image Interpretation, Computer-Assisted
Retrospective Studies
Sensitivity and Specificity
Thigh / radiography
Tomography, X-Ray Computed / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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