| Comparison of atracurium and succinylcholine for electroconvulsive therapy in a patient with atypical plasma cholinesterase. | |
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MedLine Citation:
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PMID: 3581397 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Succinylcholine 2-5 mg or atracurium 10-15 mg were given on five separate occasions to a 24-year-old, 64 kg woman homozygous for atypical plasma cholinesterase who was undergoing electroconvulsive therapy (ECT). Atracurium blockade was reversed with atropine, 0.6 mg and edrophonium, 35 mg. Train-of-four stimulation was applied to the ulnar nerve and the force of contraction of the adductor pollicis muscle was recorded. Doses producing 90 per cent first twitch blockade were 2.5 and 15 mg for succinylcholine and atracurium respectively. The onset of action was 6 min for both relaxants, and time to 90 per cent first twitch recovery was 20 min for succinylcholine and 16 min for the atracurium-edrophonium combination. It is concluded that the use of atracurium in these patients does not offer marked advantages over small doses of succinylcholine. |
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Authors:
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D R Hickey; J P O'Connor; F Donati |
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Publication Detail:
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Type: Case Reports; Comparative Study; Journal Article |
Journal Detail:
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Title: Canadian journal of anaesthesia = Journal canadien d'anesthésie Volume: 34 ISSN: 0832-610X ISO Abbreviation: Can J Anaesth Publication Date: 1987 May |
Date Detail:
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Created Date: 1987-07-14 Completed Date: 1987-07-14 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8701709 Medline TA: Can J Anaesth Country: CANADA |
Other Details:
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Languages: eng Pagination: 280-3 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Atracurium / administration & dosage* Cholinesterases / blood*, genetics Electroconvulsive Therapy* Female Homozygote Humans Schizophrenia, Catatonic / therapy Succinylcholine / administration & dosage* |
| Chemical | |
Reg. No./Substance:
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306-40-1/Succinylcholine; 64228-79-1/Atracurium; EC 3.1.1.8/Cholinesterases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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