| Comparison of assisted reproductive technology performance after oocyte retrieval under general anaesthesia (propofol) versus paracervical local anaesthetic block: a case-controlled study. | |
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MedLine Citation:
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PMID: 9806267 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Propofol (Dipirivan) is an intravenous anaesthetic drug used for general anaesthesia. Although frequently used as a general anaesthetic for ultrasound procedures, its use during transvaginal oocyte retrieval is currently being debated. A total of 202 patients undergoing fertility treatment was included in a prospective, matched, controlled study, in which we compared fertilization rates and embryo development in terms of morphological quality and speed of development and the implications for reproductive outcome and pregnancy following general anaesthesia using either propofol or a paracervical local anaesthetic block during oocyte collection. There were no differences between the fertilization rates and the embryo cleavage characteristics for the two groups. The initial implantation rate per transferred embryo after general anaesthesia was similar to that after paracervical local anaesthetic block (13.4 versus 18.6%; P = 0.10). The ongoing clinical implantation rates per embryo transferred were also similar in the two groups. |
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Authors:
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F Christiaens; C Janssenswillen; A C Van Steirteghem; P Devroey; C Verborgh; F Camu |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article |
Journal Detail:
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Title: Human reproduction (Oxford, England) Volume: 13 ISSN: 0268-1161 ISO Abbreviation: Hum. Reprod. Publication Date: 1998 Sep |
Date Detail:
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Created Date: 1999-01-21 Completed Date: 1999-01-21 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8701199 Medline TA: Hum Reprod Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 2456-60 Citation Subset: IM |
Affiliation:
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Department of Anaesthesiology, University Hospital, Dutch-speaking Brussels Free University (Vrije Universiteit Brussel), Belgium. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anesthesia, General Anesthesia, Obstetrical Anesthetics, Intravenous / administration & dosage* Case-Control Studies Female Fertilization in Vitro / methods* Humans Infertility, Female / therapy Oocyte Donation / methods* Pregnancy Pregnancy Rate Propofol / administration & dosage* |
| Chemical | |
Reg. No./Substance:
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0/Anesthetics, Intravenous; 2078-54-8/Propofol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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