| Comparison of antiviral efficiency of immune responses in shrimp. | |
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MedLine Citation:
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PMID: 18721886 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The antiviral effectiveness of three major immune responses including phagocytosis, apoptosis and proPO system in the shrimp Marsupenaeus japonicus was characterized. It was found that the suppression of apoptosis and phagocytosis in vivo by their corresponding inhibitors resulted in the increase of white spot syndrome virus (WSSV) copies and shrimp mortality, whereas the inhibition of phenol oxidase generated the least influence on WSSV infection and shrimp mortality. These results suggest that apoptosis and phagocytosis were the essential immune responses to protect shrimp from virus infection, while the phenol-oxidase-dependent proPO system plays a comparatively minor role in antiviral defense of shrimp. |
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Authors:
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Wei Wang; Xiaobo Zhang |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-08-05 |
Journal Detail:
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Title: Fish & shellfish immunology Volume: 25 ISSN: 1050-4648 ISO Abbreviation: Fish Shellfish Immunol. Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-11-05 Completed Date: 2009-01-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9505220 Medline TA: Fish Shellfish Immunol Country: England |
Other Details:
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Languages: eng Pagination: 522-7 Citation Subset: IM |
Affiliation:
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Key Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, State Oceanic Administration, Xiamen 361005, People's Republic of China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Apoptosis DNA Virus Infections / immunology* Immune System / physiology* Immunosuppressive Agents / pharmacology Monophenol Monooxygenase / antagonists & inhibitors Penaeidae / drug effects, immunology*, virology* Phagocytosis White spot syndrome virus 1* |
| Chemical | |
Reg. No./Substance:
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0/Immunosuppressive Agents; EC 1.14.18.1/Monophenol Monooxygenase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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